Molecular Tuning for Vaccine Immunity: Regulating Immune and Inflammatory Responses to Inform Vaccine Design

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccine Design, Development, and Delivery".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 91

Special Issue Editors


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Guest Editor
Faculty of Health, School of Medicine, Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Australia
Interests: host-pathogen interaction; innate immunity; vaccinology; virology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea
Interests: immunology; virology; microbiology; antiviral activity

Special Issue Information

Dear Colleagues,

Vaccination remains one of the most effective strategies to prevent infectious diseases, yet the molecular basis of virulence factors that guide vaccine design is not fully understood. This Special Issue, “Molecular Tuning for Vaccine Immunity: Regulating Immune and Inflammatory Responses to Inform Vaccine Design”, focuses on the mechanisms that shape immune activation, regulation, and memory to inform vaccine development.

We invite original research articles, reviews, short communications, and perspectives that examine immune signaling pathways, inflammatory control, and host pathogen interactions relevant to vaccination. Submissions may include studies on antigen processing and presentation, adjuvant mechanisms, cytokine and chemokine networks, and the coordination between innate and adaptive immunity. Work addressing post translational regulation, including ubiquitin mediated processes, and their impact on immune responses is particularly encouraged.

Both experimental and computational approaches are welcome, including molecular and cellular studies, in vivo models, and systems level analyses using advanced technologies. Contributions that provide mechanistic insight into immune modulation and factors influencing vaccine efficacy and durability are especially suitable for submission. Collectively, this Special Issue aims to advance fundamental understanding and support the development of improved vaccination strategies.

Dr. Kiramage Chathuranga
Dr. Asela Weerawardhana
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccine immunity
  • immune signaling pathways
  • inflammatory signaling
  • host–pathogen interactions
  • innate and adaptive immunity
  • post-translational modifications
  • immune regulation
  • cytokines and chemokines

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Published Papers

This special issue is now open for submission.
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