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TropicalMed
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Innovative Approaches to Combat Infectious Diseases in Low and Middle...
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Innovative Approaches to Combat Infectious Diseases in Low and Middle Income Countries (LMICs): Epidemiology, Diagnosis, and Interventions

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Infectious Diseases".

Deadline for manuscript submissions: 9 January 2026 | Viewed by 883

Special Issue Editors

Dr. Bayodé Roméo Adégbitè

E-Mail Website
Guest Editor
1. Centre de Recherches médicales de Lambaréné (CERMEL), 86FJ+39W, Lambaréné, Gabon
2. Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Interests: infectious diseases; public health; comorbidities; control
Prof. Dr. Michael Ramharter

E-Mail Website
Guest Editor
1. Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Straße 74, D-20359 Hamburg, Germany
2. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251 Hamburg, Germany
Interests: parasitology; tropical medicine; emerging viral infection

Special Issue Information

Dear Colleagues,

This Special Issue aims to bring together cutting-edge research and innovative approaches to tackle the pressing challenges posed by tuberculosis, HIV, malaria, parasitic infection, and other communicable diseases of interest in LIMCs.

Scope and Topics:

This Special Issue will cover a wide range of topics, including but not limited to:

  • Epidemiology: Studies on the distribution, determinants, and control of tropical infections and infectious diseases.
  • Diagnosis: Advances in diagnostic techniques, tools, and methodologies for early and accurate detection of tropical infections.
  • Treatment: Innovative treatment strategies, drug development, and therapeutic interventions for managing tropical infections.
  • Interventions: Innovative interventions, operational research, vaccination programs, or community-based approaches to prevent, treat, manage, or control the spread of infectious diseases.

Submission Guidelines:

We invite researchers, clinicians, and public health professionals to submit original research articles and reviews that align with this Special Issue's theme. Manuscripts should be prepared according to the journal's guidelines and submitted through the journal's online submission system.

We look forward to your valuable contributions to this Special Issue, which will undoubtedly advance our understanding and control of tropical infections and infectious diseases.

Sincerely,

Dr. Bayodé Roméo Adégbitè
Prof. Dr. Michael Ramharter
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epidemiology
  • diagnosis
  • treatment
  • interventions
  • tropical infections
  • infectious diseases
  • public health
  • vaccination
  • drug development
  • community health

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  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

14 pages, 2808 KB  
Article
Polyparasitic Infections: Associated Factors and Effect on the Haemoglobin Level of Children Living in Lambaréné Remote and Surrounding Rural Areas from Gabon—A Cross-Sectional Study
by Paul Alvyn Nguema-Moure, Bayode Romeo Adegbite, Moustapha Nzamba Maloum, Jean-Claude Dejon-Agobé, Roméo-Aimé Laclong Lontchi, Yabo Josiane Honkpehedji, Danny-Carrel Manfoumbi Mabicka, Christian Chassem-Lapue, Pavel Warry Sole, Stephane Ogoula, Fabrice Beral M’Baidigium, Jenny Mouloungui-Mavoungou, Michael Ramharter, Peter Gottfried Kremsner and Ayôla Akim Adegnika
Trop. Med. Infect. Dis. 2025, 10(8), 218; https://doi.org/10.3390/tropicalmed10080218 - 31 Jul 2025
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Abstract
Background: Polyparasitic infections remain widespread in endemic regions, yet its contributing factors and health impact are not well understood. This study aims to estimate the prevalence and associated factors and examines the effect of polyparasitic infection on haemoglobin levels among children. Methods: A [...] Read more.
Background: Polyparasitic infections remain widespread in endemic regions, yet its contributing factors and health impact are not well understood. This study aims to estimate the prevalence and associated factors and examines the effect of polyparasitic infection on haemoglobin levels among children. Methods: A cross-sectional study was conducted in Lambaréné, Gabon, among children aged 2–17 years from November 2019 to December 2020. Haemoglobin levels, environmental conditions, and sociodemographic data were collected. Stool, urine, and blood samples were analysed using light microscopy for parasite detection. Factors associated with polyparasitism were explored. Results: Out of 656 participants, 65.4% had at least one infection, with intestinal protozoa species (21.3%), Trichuris trichiura (33%), Ascaris lumbricoides (22%), Schistosoma haematobium (20%), and Plasmodium falciparum (10%) being the most common. Polyparasitic infection was identified in 26% of children, mostly as bi-infections (69.2%), and was negatively associated with haemoglobin levels (β = −0.06). Conclusions: These findings emphasise the burden of polyparasitic infections and adverse health effects in Lambaréné, Gabon. Full article
(This article belongs to the Special Issue Innovative Approaches to Combat Infectious Diseases in Low and Middle Income Countries (LMICs): Epidemiology, Diagnosis, and Interventions)
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17 pages, 621 KB  
Article
The Impact of a Community Pharmacy-Led Deworming-Related Counselling Service: An Interventional Study in a Low-to-Middle Income Country
by Amira B. Kassem, Ahmad Z. Al Meslamani, Mohamed AbdElrahman, Nadia Al Mazrouei, Sherouk M. Okda, Noha A. El-Bassiouny, Asmaa Abdel-hamed Hamedo, Doaa Abdelrazek Shaban, Dina Fathy Elsmadessy, Ammena Y. Binsaleh, Asmaa Saleh and Hebatallah Ahmed Mohamed Moustafa
Trop. Med. Infect. Dis. 2025, 10(8), 215; https://doi.org/10.3390/tropicalmed10080215 - 30 Jul 2025
Viewed by 347
Abstract
Background: Since the current increase in antimicrobial resistance globally, parasitic infectious diseases have become a greater public health crisis than ever before and an absolute priority. The Egyptian community pharmacist, as a health care provider and advisor, has a potential role to play [...] Read more.
Background: Since the current increase in antimicrobial resistance globally, parasitic infectious diseases have become a greater public health crisis than ever before and an absolute priority. The Egyptian community pharmacist, as a health care provider and advisor, has a potential role to play in deworming. Objective: To evaluate the outcomes of community pharmacist-led deworming-related counseling services. Methods: A prospective randomized controlled study was conducted in Damanhur, Behera, Egypt. The intervention group received community pharmacy counseling, and the control group received the usual care. Both groups were monitored for 12 months for recurrence evaluation. Results: A total of 173 patients were included, of whom 96 (55.5%) received patient counseling. The types of infection included Oxyuris (44.5%), Entamoeba histolytica (28.9%), Ascaris (8.7%), Entamoeba Cyst (8.7%), Giardiasis (4.6%), Schistosomiasis (2.9%), and pinworm (1.7%). A total of 119 participants (68.8%) reported a need for dose repetition. Personal hygiene practices were reported by 71 participants (41%). Recurrence of infection was observed in 101 cases (58.4%). Patient counseling was significantly associated with lower recurrence rates and higher rates of personal hygiene application (p < 0.001). Multivariate logistic regression analysis revealed that patient counseling and personal hygiene measures were the only significant predictors of infection recurrence rate. Conclusions: Community pharmacists’ deworming-related counseling had positive behavioral and clinical outcomes. Full article
(This article belongs to the Special Issue Innovative Approaches to Combat Infectious Diseases in Low and Middle Income Countries (LMICs): Epidemiology, Diagnosis, and Interventions)
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