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Special Issue "Medically Relevant Snake Toxins, Current Antivenoms and the Development of Next-Generation Antivenoms"
Deadline for manuscript submissions: closed (31 January 2020).
Snake venoms are complex mixtures of numerous protein and polypeptide toxins belonging to only a few major molecular families. These toxin families include several classes of enzymes such as serine proteases, metalloproteases, phospholipases A2, and L-amino acid oxidases. Venom also contains numerous bioactive polypeptides that lack enzymatic activity, such as the three-finger toxins, myotoxins, disintegrins, C-type lectins, CRISP (cysteine-rich secretory protein) toxins, growth factors, and protease inhibitors, such as cystatin and Kunitz-type protease inhibitors. Snake envenoming can result in significant injury and in many cases death. A shortage of antivenoms is creating a global crisis that has encouraged health providers and researchers to take heed. The evolutionary relatedness among snake venom toxins and the high global morbidity and mortality has incited an interest in developing broad toxin class specificity antivenoms.
This Special Issue of Toxins aims to provide information on medically relevant snake toxins related to their chemical, pharmacological, pathophysiological, and immunological properties and their ability to be neutralized by current commercial antivenoms, including but not limited to the recent advancements of next-generation antivenom development and their ability to potentially alleviate this neglected tropical disease, snake envenoming.
Dr. Elda E. Sánchez
Dr. Montamas Suntravat
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Snake venoms
- phospholipases A2
- next generation antivenoms
- neglected tropical diseases