Special Issue "Mycotoxins and Their Metabolites Biochemistry, Molecular Biology and Toxicology"
Deadline for manuscript submissions: 31 December 2021.
2. Biomedical Research Center, University Hospital Hradec Kralove, 50005 Hradec Kralove, Czech Republic
Interests: drug design and development; antidotes for pesticide and nerve agent intoxications; Alzheimer’s disease; detergents as disinfectants, decontamination means; toxins; nanotechnology; project management; scientific management; technology transfer; health economics and pharmacoeconomics
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Interests: toxin; synthetic toxins; natural toxin; toxic industrial chemicals; chemical warfare agents; antidotes; signalling pathway; molecular biology; in vitro & in vivo; biochemistry
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Mycotoxins comprise hundreds of toxic secondary metabolites that are produced by fungi and contaminate cereal grains, leading to serious effects on human and animal health. Pathophysiologic effects associated with mycotoxins include immunosuppression, altered neuroendocrine signaling, proinflammatory gene induction, malnutrition, disruption of the growth hormone axis, carcinogenesis, and reproductive and teratogenic effects. Exposure routes, bioavailability, and potential accumulation of mycotoxins in different species or organs can lead to different toxicities. Although the toxicity of most metabolites has been reduced compared with the original mycotoxins, they are still extremely harmful to humans and animals, suggesting that further investigations into toxicity are necessary. As more and more novel mycotoxins and metabolites are discovered, there is increasing interest in studying the toxicity and molecular mechanisms of these toxins and their major metabolites. This Special Issue of Toxins is focused on new insights and advances in cellular and molecular mechanisms of toxicity induced by mycotoxins and their major metabolites, especially from biochemistry and signaling pathways that underlie these toxic responses. While the focus is on molecular biology and toxicology of mycotoxins and metablites, manuscripts addressing the occurrence, contamination, and risk assessment of novel mycotoxins and metabolites will also be considered.
Prof. Dr. Kamil Kuca
Prof. Qinghua Wu
Dr. Eugenie Nepovimova
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- molecular mechanisms