Whole-Cell Biosensor: Recent Advances

Dear Colleagues,

The fabrication of whole-cell biosensors is a fascinating direction in bioanalytical chemistry. Arguably, whole-cell biosensors represent the most interesting and intriguing part of the biosensor family. In whole-cell biosensorx, we benefit from the analytical response of the cellular machinery orchestrated by the synergy of nucleic acids and enzymes. Essentially, the simplest (yet fully functional) whole-cell biosensors do not even require any physical transdusers, relying on direct observations of cellular responses to various analytes manifested in luminescence intensity changes or similar signals. More elaborate devices, in general, follow the classical biosensor setup structure, where the biological sensing elements (live cells) are incorporated into a certain electronic device capable of sensing the (bio)chemical changes within the cells. This opens avenues for the effective and selective detection of various analytes. Therefore, whole-cell biosensors hold great promise in current bioanalytical chemistry, attracting the attention of researchers worldwide.

This Special Issue is focused on recent advances in the field of whole-cell biosensors. Both review and original research articles are invited. In addition to papers reporting on the fabrication and applications of whole-cell biosensors, contributions featuring other areas related to whole-cells biosensors, such as genetic modifications of reporter cells, cell immobilization, or cell surface modifications. In addition, manuscripts reporting technological advances towards more effective whole-cell biosensors, such as the development of novel analytical platforms, the improvement of data acquisition, or the introduction of novel measurements or data processing techniques, will be considered.

Dr. Rawil Fakhrullin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.