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Photoacoustic and Ultrasound Imaging and Sensors for Medical Diagnosis

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A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 4719

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Special Issue Editors

Prof. Dr. Changhan Yoon

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Guest Editor

1. Department of Biomedical Engineering, Inje University, Gimhae 50834, Republic of Korea
2. Department of Nanoscience and Engineering, Inje University, Gimhae 50834, Republic of Korea
Interests: ultrasound imaging; molecular imaging
Special Issues, Collections and Topics in MDPI journals

Dr. Hae Gyun Lim

E-Mail Website
Guest Editor

Department of Biomedical Engineering, Pukyong National University, 45, Yongso-ro, Nam-gu, Busan 48513, Republic of Korea
Interests: ultrasound imaging; ultrasound sensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of ultrasonic sensors and imaging technologies has greatly contributed to the improvement of diagnostic capabilities of ultrasound and photoacoustic imaging for medical applications. Medical ultrasound and photoacoustic imaging in particular are continuously evolving with recent advances in other area. This Special Issue aims to publish all recent research and developments of photoacoustic and ultrasound imaging systems and their applications in the medical field.

The suggested topics include but are not limited to:

High-resolution ultrasound and photoacoustic imaging technologies;
Novel ultrasound and photoacoustic imaging systems;
Novel ultrasonic transducers for ultrasound and photoacoustic imaging;
Deep-learning-based image reconstruction and diagnosis;
Preclinical and clinical applications.

Prof. Dr. Changhan Yoon
Dr. Hae Gyun Lim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

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Research

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14 pages, 7359 KiB

Open AccessArticle

Effect of Clutter Filter in High-Frame-Rate Ultrasonic Backscatter Coefficient Analysis

by Masaaki Omura, Kunimasa Yagi, Ryo Nagaoka, Kenji Yoshida, Tadashi Yamaguchi and Hideyuki Hasegawa

Sensors 2023, 23(5), 2639; https://doi.org/10.3390/s23052639 - 27 Feb 2023

Cited by 1 | Viewed by 1479

Abstract

High-frame-rate imaging with a clutter filter can clearly visualize blood flow signals and provide more efficient discrimination with tissue signals. In vitro studies using clutter-less phantom and high-frequency ultrasound suggested a possibility of evaluating the red blood cell (RBC) aggregation by analyzing the frequency dependence of the backscatter coefficient (BSC). However, in in vivo applications, clutter filtering is required to visualize echoes from the RBC. This study initially evaluated the effect of the clutter filter for ultrasonic BSC analysis for in vitro and preliminary in vivo data to characterize hemorheology. Coherently compounded plane wave imaging at a frame rate of 2 kHz was carried out in high-frame-rate imaging. Two samples of RBCs suspended by saline and autologous plasma for in vitro data were circulated in two types of flow phantoms without or with clutter signals. The singular value decomposition was applied to suppress the clutter signal in the flow phantom. The BSC was calculated using the reference phantom method, and it was parametrized by spectral slope and mid-band fit (MBF) between 4–12 MHz. The velocity distribution was estimated by the block matching method, and the shear rate was estimated by the least squares approximation of the slope near the wall. Consequently, the spectral slope of the saline sample was always around four (Rayleigh scattering), independently of the shear rate, because the RBCs did not aggregate in the solution. Conversely, the spectral slope of the plasma sample was lower than four at low shear rates but approached four by increasing the shear rate, because the aggregations were presumably dissolved by the high shear rate. Moreover, the MBF of the plasma sample decreased from

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36 to

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49 dB in both flow phantoms with increasing shear rates, from approximately 10 to 100 s⁻¹. The variation in the spectral slope and MBF in the saline sample was comparable to the results of in vivo cases in healthy human jugular veins when the tissue and blood flow signals could be separated. Full article

(This article belongs to the Special Issue Photoacoustic and Ultrasound Imaging and Sensors for Medical Diagnosis)

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Review

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21 pages, 3271 KiB

Open AccessReview

Design of Preamplifier for Ultrasound Transducers

by Hojong Choi

Sensors 2024, 24(3), 786; https://doi.org/10.3390/s24030786 - 25 Jan 2024

Viewed by 1042

Abstract

In diagnostic ultrasound imaging applications, preamplifiers are used as first-stage analog front-end amplifiers for ultrasound transducers because they can amplify weak acoustic signals generated directly by ultrasound transducers. For emerging diagnostic ultrasound imaging applications, different types of preamplifiers with specific design parameters and circuit topologies have been developed, depending on the types of the ultrasound transducer. In particular, the design parameters of the preamplifier, such as the gain, bandwidth, input- or output-referred noise components, and power consumption, have a tradeoff relationship. Guidelines on the detailed design concept, design parameters, and specific circuit design techniques of the preamplifier used for ultrasound transducers are outlined in this paper, aiming to help circuit designers and academic researchers optimize the performance of ultrasound transducers used in the diagnostic ultrasound imaging applications for research directions. Full article

(This article belongs to the Special Issue Photoacoustic and Ultrasound Imaging and Sensors for Medical Diagnosis)

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Other

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20 pages, 5207 KiB

Open AccessSystematic Review

The Role of Ultrasound in Cancer and Cancer-Related Pain—A Bibliometric Analysis and Future Perspectives

by Badrinathan Sridharan, Alok Kumar Sharma and Hae Gyun Lim

Sensors 2023, 23(16), 7290; https://doi.org/10.3390/s23167290 - 21 Aug 2023

Cited by 3 | Viewed by 1720

Abstract

Ultrasound has a deep penetrating ability with minimal or no tissue injury, while cancer-mediated complications during diagnosis, therapy, and surgery have become a serious challenge for clinicians and lead to the severity of the primary condition (cancer). The current study highlights the importance of ultrasound imaging and focused ultrasound therapy during cancer diagnosis, pain reduction, guidance for surgical resection of cancer, and the effectiveness of chemotherapy. We performed the bibliometric analysis on research domains involving ultrasound, cancer management, pain, and other challenges (chemotherapy, surgical guidance, and postoperative care), to observe the trend by which the research field has grown over the years and propose a possible future trend. The data was obtained from the Web of Science, processed, and exported as plain text files for analysis in the Bibliometrix R web interface using the Biblioshiny package. A total of 3248 documents were identified from 1100 journal sources. A total of 390 articles were published in 2022, with almost a 100% growth rate from previous years. Based on the various network analysis, we conclude that the outcome of the constant research in this domain will result in better patient care during the management of various diseases, including cancer and other co-morbidities. Full article

(This article belongs to the Special Issue Photoacoustic and Ultrasound Imaging and Sensors for Medical Diagnosis)

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