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Feature Review Papers in the Biomedical Sensors Section
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Feature Review Papers in the Biomedical Sensors Section

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 11789

Special Issue Editor

Prof. Dr. James F. Rusling

E-Mail Website
Guest Editor
1. Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA
2. Department of Surgery and Neag Cancer Center, Uconn Health, Farmington, CT 06030-0001, USA
Interests: biomedical diagostics; bioelectrochemistry; bioanalytical chemistry; biosensors and arrays; genotoxicity analysia; electrochemical catalysis; computer data analysis; automation; biocatalysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Many new concepts and designs for biomedical sensors have appeared since the development of the first successful enzyme-based glucose sensors developed in the 1980s, and these sensors are now used worldwide by diabetic patients. New biosensor areas, among others, include in vivo sensors for heart health, other in vivo sensors, devices that measure protein and nucleic acid biomarkers for diseases such as cancer and heart disease and others including blood and tissue, optical and other sensors for specific detection in single cells, as well as other areas. Microfluidic systems have also played a role, often in the preparation of test systems for measurements since, often, these new developments are slow to find their way into medical practice. Also of interest is the successful application of new sensor technologies in the clinic since new technologies often experience long delays before successful implementation to patients. This Special Issue welcomes the submission of review articles to Sensors describing recent advances in biomedical sensors, including recently developed devices and their applications, as well as the clinical application of these new systems.

Prof. Dr. James F. Rusling
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • in vivo sensors
  • cancer biomarkers
  • heart disease biomarkers
  • Alzheimer’s disease biomarkers
  • sensors for physiological function
  • self-powered sensors
  • RNA sensors
  • CRISPR-based sensors
  • multiplexed sensors
  • wearable sensors
  • implanted sensors
  • nano-electronically powered sensors

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Review

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18 pages, 1283 KiB  
Review
Sensors in Bone: Technologies, Applications, and Future Directions
by Afreen Anwar, Taruneet Kaur, Sachin Chaugule, Yeon-Suk Yang, Aryan Mago, Jae-Hyuck Shim and Aijaz Ahmad John
Sensors 2024, 24(19), 6172; https://doi.org/10.3390/s24196172 - 24 Sep 2024
Viewed by 5375
Abstract
Osteoporosis, a prevalent ailment worldwide, compromises bone strength and resilience, particularly afflicting the elderly population. This condition significantly heightens susceptibility to fractures even from trivial incidents, such as minor falls or impacts. A major challenge in diagnosing osteoporosis is the absence of discernible [...] Read more.
Osteoporosis, a prevalent ailment worldwide, compromises bone strength and resilience, particularly afflicting the elderly population. This condition significantly heightens susceptibility to fractures even from trivial incidents, such as minor falls or impacts. A major challenge in diagnosing osteoporosis is the absence of discernible symptoms, allowing osteoporosis to remain undetected until the occurrence of a fracture event. Early symptom detection and swift diagnosis are critical for preventing severe issues related to bone diseases. Assessing bone turnover markers aids in identifying, diagnosing, and monitoring these conditions, guiding treatment decisions. However, conventional techniques for measuring bone mineral density are costly, time-consuming, and require specialized expertise. The integration of sensor technologies into medical practices has transformed how we monitor, diagnose, and treat various health conditions, including bone health and orthopedics. This review aims to provide a comprehensive overview of the current state of sensor technologies used in bone, covering their integration with bone tissue, various applications, recent advancements, challenges, and future directions. Full article
(This article belongs to the Special Issue Feature Review Papers in the Biomedical Sensors Section)
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18 pages, 2146 KiB  
Review
Implantable Pressure-Sensing Devices for Monitoring Abdominal Aortic Aneurysms in Post-Endovascular Aneurysm Repair
by Nuno P. Silva, Bilal Amin, Eoghan Dunne, Niamh Hynes, Martin O’Halloran and Adnan Elahi
Sensors 2024, 24(11), 3526; https://doi.org/10.3390/s24113526 - 30 May 2024
Cited by 2 | Viewed by 2325
Abstract
Over the past two decades, there has been extensive research into surveillance methods for the post-endovascular repair of abdominal aortic aneurysms, highlighting the importance of these technologies in supplementing or even replacing conventional image-screening modalities. This review aims to provide an overview of [...] Read more.
Over the past two decades, there has been extensive research into surveillance methods for the post-endovascular repair of abdominal aortic aneurysms, highlighting the importance of these technologies in supplementing or even replacing conventional image-screening modalities. This review aims to provide an overview of the current status of alternative surveillance solutions for endovascular aneurysm repair, while also identifying potential aneurysm features that could be used to develop novel monitoring technologies. It offers a comprehensive review of these recent clinical advances, comparing new and standard clinical practices. After introducing the clinical understanding of abdominal aortic aneurysms and exploring current treatment procedures, the paper discusses the current surveillance methods for endovascular repair, contrasting them with recent pressure-sensing technologies. The literature on three commercial pressure-sensing devices for post-endovascular repair surveillance is analyzed. Various pre-clinical and clinical studies assessing the safety and efficacy of these devices are reviewed, providing a comparative summary of their outcomes. The review of the results from pre-clinical and clinical studies suggests a consistent trend of decreased blood pressure in the excluded aneurysm sac post-repair. However, despite successful pressure readings from the aneurysm sac, no strong link has been established to translate these measurements into the presence or absence of endoleaks. Furthermore, the results do not allow for a conclusive determination of ongoing aneurysm sac growth. Consequently, a strong clinical need persists for monitoring endoleaks and aneurysm growth following endovascular repair. Full article
(This article belongs to the Special Issue Feature Review Papers in the Biomedical Sensors Section)
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Other

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23 pages, 588 KiB  
Systematic Review
The Role of Biomarkers in Monitoring Chronic Fatigue Among Male Professional Team Athletes: A Systematic Review
by Alejandro Soler-López, Adrián Moreno-Villanueva, Carlos D. Gómez-Carmona and José Pino-Ortega
Sensors 2024, 24(21), 6862; https://doi.org/10.3390/s24216862 - 25 Oct 2024
Cited by 1 | Viewed by 3431
Abstract
This systematic review synthesizes evidence on biomarker responses to physiological loads in professional male team sport athletes, providing insights into induced fatigue states. Structured searches across major databases yielded 28 studies examining various biomarkers in elite team sport players. Studies evaluated muscle damage [...] Read more.
This systematic review synthesizes evidence on biomarker responses to physiological loads in professional male team sport athletes, providing insights into induced fatigue states. Structured searches across major databases yielded 28 studies examining various biomarkers in elite team sport players. Studies evaluated muscle damage markers, anabolic/catabolic hormones reflecting metabolic strain, inflammatory markers indicating immune activity and tissue damage, immunological markers tied to infection risk, and oxidative stress markers showing redox imbalances from excessive physiological load. Responses were examined in official matches and training across competitive seasons. The evidence shows that professional team sports induce significant alterations in all studied biomarkers, reflecting measurable physiological strain, muscle damage, oxidative stress, inflammation, and immunosuppression during intensive exercise. These effects tend to be larger and more prolonged after official matches compared to training. Reported recovery time courses range from 24-h to several days post-exercise. Monitoring biomarkers enables quantifying cumulative fatigue and physiological adaptations to training/competition loads, helping to optimize performance while mitigating injury and overtraining. Key biomarkers include creatine kinase, testosterone, cortisol, testosterone/cortisol ratio, salivary immunoglobulin-A, and markers of inflammation and oxidative stress. Further research should extend biomarker monitoring to cover psychological stress and affective states alongside physiological metrics for deeper insight into athlete wellness and readiness. Full article
(This article belongs to the Special Issue Feature Review Papers in the Biomedical Sensors Section)
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