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Applications of Polymer Biomedical Materials in Medicine and Dentistry

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 2880

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Guest Editor
School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
Interests: dentistry; materials science; polymeric materials; ceramic materials; adhesive dentistry; fatigue and fracture analysis; dental materials; prosthodontics
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Special Issue Information

Dear Colleagues,

In recent years, polymer biomedical materials have attracted increasing attention, especially in the fields of medicine and dentistry. These versatile materials have a wide range of applications, from implants and prosthetics to drug delivery systems, making them invaluable in driving modern healthcare solutions. Many studies have examined their interfacial properties, adhesive bonding, physicochemical and mechanical performance, and biocompatibility, contributing to the rapidly growing body of literature.

The desirable properties of high-performance polymer biomedical materials, such as their mechanical strength, chemical resistance, and radiolucency, make them an attractive alternative to traditional materials in medical and dental applications. Recent research has highlighted exciting advancements, including surface modification techniques that enhance bioactivity, fiber reinforcement to improve mechanical performance, and the integration of 3D printing technologies, artificial intelligence, or big data for customized, patient-specific solutions. Furthermore, the potential of polymer biomedical materials in controlled drug delivery has opened innovative pathways, further expanding their utility in clinical practice in medicine and dentistry.

Given these rapid developments, this Special Issue aims to present high-quality research showcasing recent advances in polymeric biomedical materials, with a special focus on their applications in medicine and dentistry.

Dr. Tzu-Yu Peng
Guest Editor

Manuscript Submission Information

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Keywords

  • polyetheretherketone
  • high-performance polymers
  • surface modification
  • adhesive bonding
  • physicochemical properties
  • drug delivery
  • biological response
  • additive manufacturing
  • CAD/CAM
  • digital workflow
  • artificial intelligence
  • big data

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Published Papers (1 paper)

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Research

16 pages, 7959 KiB  
Article
Synergistic Effect of Strontium Doping and Surfactant Addition in Mesoporous Bioactive Glass for Enhanced Osteogenic Bioactivity and Advanced Bone Regeneration
by Ya-Yi Chen, Tien-Li Ma, Pei-Jung Chang, Yuh-Jing Chiou, Wei-Min Chang, Ci-Fen Weng, Chin-Yi Chen, Yu-Kang Chang and Chung-Kwei Lin
Polymers 2025, 17(2), 187; https://doi.org/10.3390/polym17020187 - 14 Jan 2025
Viewed by 819
Abstract
Mesoporous bioactive glass (MBG) is an advanced biomaterial widely recognized for its application in bone regenerative engineering. This study synthesized an MBG powder (80 mol% SiO2, 5 mol% P2O5, and 15 mol% CaO) using a facile sol-gel [...] Read more.
Mesoporous bioactive glass (MBG) is an advanced biomaterial widely recognized for its application in bone regenerative engineering. This study synthesized an MBG powder (80 mol% SiO2, 5 mol% P2O5, and 15 mol% CaO) using a facile sol-gel method with the non-ionic surfactant Pluronic® P123, which acted as a pore-forming agent. MBGs form bioactive surfaces that facilitate HA formation, and the presence of Pluronic® P123 increases the surface area and promotes HA nucleation. Various percentages of strontium (Sr) doping were examined to improve bioreactivity, biological response, and bone formation, with 3SMBG (3 mol% Sr) showing the highest specific surface area. In vitro biocompatibility tests revealed HA formation on all glass surfaces after immersion in simulated body fluid (SBF), indicated by sheet-like HA morphologies, the presence of PO43− and CO32− functional groups, and the amorphous structure along with SrCO3 crystalline phases corresponding to HA and Sr-HA structures. Sr doping resulted in delayed initial degradation and sustained release of Sr2+, achieving over 95% cell viability. Surfactant-induced mesoporous structure and Sr incorporation synergistically enhance osteocyte induction and formation in vitro. These findings suggest that Sr-doped MBG, particularly with P123-assisted Sr/Ca substitution, optimizes the material’s properties for advanced bone regenerative applications. Full article
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