Oxidative Stress and Inflammation in Metabolic Diseases: Therapeutic Roles of Plant Natural Products
A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 91
Special Issue Editors
Interests: functional food; toxicology; metabolic diseases; natural products
Special Issues, Collections and Topics in MDPI journals
Interests: functional food; diabetes; oxidative stress; medicinal plant
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic diseases, including diabetes, obesity, and cardiovascular disorders, are increasingly prevalent and are often driven by oxidative stress and chronic inflammation. These interconnected biological processes exacerbate disease progression, leading to severe complications. Oxidative stress results from an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defense mechanisms, while inflammation contributes to tissue damage and dysfunction. Together, these factors play pivotal roles in the pathogenesis of various metabolic disorders, posing significant challenges for effective treatment.
Plant natural products, including phytochemicals, plant-based functional foods, and nutraceuticals, have garnered attention as promising therapeutic agents due to their antioxidative and anti-inflammatory properties. These bioactive compounds are seen as effective complementary treatments with minimal toxicity, offering a holistic approach to managing oxidative stress-related metabolic diseases. Evidence suggests that certain plant-derived products can modulate oxidative pathways and inflammatory responses, presenting an opportunity for alternative or adjunctive therapies in the management of these diseases.
This Special Issue invites original research articles, clinical studies, and well-written reviews that explore the therapeutic potential of plant natural products in combating oxidative stress and inflammation within the context of metabolic diseases. We aim to gather comprehensive insights into how phytochemicals and plant-based products may serve as valuable therapeutic tools in mitigating the impact of metabolic disorders, offering novel perspectives for the treatment of multifactorial diseases and bridging existing gaps in the current scientific understanding.
Dr. Ochuko Lucky Erukainure
Dr. Chika Ifeanyi Chukwuma
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- phytochemicals
- functional foods
- oxidative stress
- inflammation
- metabolic diseases
- natural plant products
- therapeutic roles
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