Bioactive Compounds from Forests: Extraction, Characterization and Functional Applications

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 551

Editor


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Guest Editor
Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China
Interests: plant-derived bioactive compounds; extraction methods; identification; bioactivities; applications

Special Issue Information

Dear Colleagues,

Forests represent a vast and largely untapped reservoir of diverse bioactive compounds with significant potential for food, pharmaceutical, nutraceutical, cosmetic, and agro-industrial applications. These natural substances—including polyphenols, terpenoids, alkaloids, polysaccharides, and other specialized metabolites—exhibit a wide range of biological activities, such as antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. This Special Issue aims to gather high-quality research, communication, protocols, and review articles that explore the latest advances in the sustainable extraction, comprehensive characterization, and functional evaluation of bioactive compounds derived from trees, shrubs, and herbs.

Topics of interest include, but are not limited to, the following:

  • Innovative and eco-friendly extraction techniques (ultrasound-assisted, microwave-assisted, ultra-high pressure-assisted, enzyme-assisted, and green solvent-based extraction);
  • Analytical methods for identification, quantification, and structural elucidation;
  • Biological activities, mechanisms of action, and structure–activity relationships;
  • Applications in pharmaceuticals, nutrition, cosmetics, and agriculture;
  • Bioavailability, stability, and delivery systems.

We welcome submissions that contribute to a deeper understanding of forest-derived bioactivities and their development into value-added products.

Prof. Dr. Chengbo Gu
Guest Editor

Manuscript Submission Information

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Keywords

  • forest bioactive compounds
  • green extraction
  • structural characterization
  • bioavailability
  • functional application

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Published Papers (1 paper)

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Research

21 pages, 1053 KB  
Article
Seasonal Dynamics of Leaf Phenolic Compounds in Rhododendron tomentosum Harmaja Growing in a Coniferous Swamp Forest
by Martyna Vengrytė and Lina Raudonė
Plants 2026, 15(14), 2195; https://doi.org/10.3390/plants15142195 - 17 Jul 2026
Viewed by 243
Abstract
Rhododendron tomentosum Harmaja is an evergreen Ericaceae species recognized as a rich source of biologically active phenolic compounds. However, information on seasonal variation in its non-volatile phenolics throughout the annual phenological cycle remains limited. Therefore, this study investigated the influence of phenological development [...] Read more.
Rhododendron tomentosum Harmaja is an evergreen Ericaceae species recognized as a rich source of biologically active phenolic compounds. However, information on seasonal variation in its non-volatile phenolics throughout the annual phenological cycle remains limited. Therefore, this study investigated the influence of phenological development on the phenolic composition of R. tomentosum leaves collected from a natural population in Lithuania between October 2023 and October 2024. Phenolic profiles were determined using a validated HPLC–PDA method. A total of 25 phenolic compounds were identified, comprising phenolic acids, flavan-3-ols, procyanidins, flavonoids, and coumarin derivatives. The highest total phenolic content was observed during autumn–winter dormancy, whereas the lowest levels occurred during fruit development. Procyanidins and phenolic acids predominated during dormancy, while flavonoids, particularly quercitrin, hyperoside, and isoquercitrin, accumulated during flowering. PCA revealed clear phenological grouping of samples and demonstrated distinct associations between dormancy and procyanidin-rich profiles and flowering and flavonoid accumulation. These findings highlight phenological stage as a key factor influencing phenolic composition and indicate optimal harvesting periods depending on the target phenolic compounds. Full article
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