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Photonics
Special Issues
New Shining Spots in Biomedical Photonics
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New Shining Spots in Biomedical Photonics

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: closed (15 November 2024) | Viewed by 2699

Special Issue Editors

Dr. Jihad Zallat

E-Mail Website
Guest Editor
The ICube Laboratory, Université de Strasbourg, Strasbourg, France
Interests: polarimetry; optical imaging; electromagnetics; biomedical imaging; remote sensing; optics; photonics; light scattering; physical modeling
Dr. Jean Rehbinder

E-Mail Website
Guest Editor
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie, Illkirch-Graffenstaden, France
Interests: polarimetry; cancer diagnosis; biomedical optics; nonlinear optics; microscopy

Special Issue Information

Dear Colleagues,

We are excited to announce a forthcoming Special Issue in Photonics dedicated to the latest and most groundbreaking developments in the realm of biomedical photonics to solve problems arising in medicine and biology.

As a multidisciplinary domain at the crossroads of physics, engineering, biology, and medicine, biomedical photonics continues to forge new frontiers in the pursuit of advancing healthcare, expanding our understanding of life, and offering a range of applications that extends from medical diagnostics to therapy and disease prevention.

This Special Issue seeks to showcase the diverse range of innovative techniques and applications that are reshaping the landscape of biomedical optics. These new shining spots might be novel approaches bringing well-established photonic techniques back into the spotlight, instrumental advancements that unlock new dimensions in our understanding of crucial cellular mechanisms, or promising emerging technologies enabled by progress in AI and quantum physics.

We welcome fundamental research, advanced technologies, and innovative applications in the form of theories, simulations, or experiments. Manuscripts will include, but are not limited to, the following topics:

  • Tissue optics;
  • Photonic devices;
  • In vivo imaging;
  • Biomedical diagnostics;
  • Biophotonics for therapeutics;
  • Biomedical imaging with AI;
  • New frontiers in biophotonics.

We invite you to join us in contributing your cutting-edge work to this Special Issue.

Dr. Jihad Zallat
Dr. Jean Rehbinder
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

17 pages, 4378 KiB  
Article
Snapshot Imaging of Stokes Vector Polarization Speckle in Turbid Optical Phantoms and In Vivo Tissues
by Daniel C. Louie, Carla Kulcsar, Héctor A. Contreras-Sánchez, W. Jeffrey Zabel, Tim K. Lee and Alex Vitkin
Photonics 2025, 12(1), 59; https://doi.org/10.3390/photonics12010059 - 11 Jan 2025
Viewed by 961
Abstract
Significance: We present a system to measure and analyze the complete polarization state distribution of speckle patterns generated from in vivo tissue. Accurate measurement of polarization speckle requires both precise spatial registration and rapid polarization state acquisition. A unique measurement system must be [...] Read more.
Significance: We present a system to measure and analyze the complete polarization state distribution of speckle patterns generated from in vivo tissue. Accurate measurement of polarization speckle requires both precise spatial registration and rapid polarization state acquisition. A unique measurement system must be designed to achieve accurate images of polarization speckle patterns for detailed investigation of the scattering properties of biological tissues in vivo. Aim and approach: This system features a polarization state analyzer with no moving parts. Two pixel-polarizer cameras allow for the instantaneous acquisition of the spatial Stokes vector distribution of polarization speckle patterns. System design and calibration methods are presented, and representative images from measurements on liquid phantoms (microsphere suspensions) and in vivo healthy and tumor murine models are demonstrated and discussed. Results and Conclusions: Quantitative measurements of polarization speckle from microsphere suspensions with controlled scattering coefficients demonstrate differences in speckle contrast, speckle size, and the degree of polarization. Measurements on in vivo murine skin and xenograft tumor tissue demonstrate the ability of the system to acquire snapshot polarization speckle images in living systems. The developed system can thus rapidly and accurately acquire polarization speckle images from different media in dynamic conditions such as in vivo tissue. This capability opens the potential for future detailed investigation of polarization speckle for in vivo biomedical applications. Full article
(This article belongs to the Special Issue New Shining Spots in Biomedical Photonics)
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11 pages, 7965 KiB  
Article
Standardizing Laser Speckle Orthogonal Contrast Imaging: Achieving Reproducible Measurements across Instruments
by Xavier Orlik, Elise Colin and Aurélien Plyer
Photonics 2024, 11(7), 585; https://doi.org/10.3390/photonics11070585 - 21 Jun 2024
Cited by 1 | Viewed by 1278
Abstract
Using two independent speckle imaging systems based on the recently published LSOCI method operating in contact mode on the skin, we assess the reproducibility of in vivo measurements and conduct an inter-instrument comparison. To this aim, we propose a calibration method to handle [...] Read more.
Using two independent speckle imaging systems based on the recently published LSOCI method operating in contact mode on the skin, we assess the reproducibility of in vivo measurements and conduct an inter-instrument comparison. To this aim, we propose a calibration method to handle each imaging system as a comprehensive unit, which includes the laser source, optics, and camera. Key to our method is the introduction of a new index that quantifies the departure of the temporal contrast observed in vivo from the spatial contrast scattered from a reference static element generating a circular Gaussian speckle field. Using such near-real-time calibration method, we demonstrate that the microcirculation images produced by 2 different instruments exhibit high accuracy and stability, with microcirculation activity values in excellent agreement, thereby paving the way for clinical applications. Full article
(This article belongs to the Special Issue New Shining Spots in Biomedical Photonics)
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