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Special Issue "Emergent Strategies for Natural Products Delivery"
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: 31 May 2020.
Interests: natural products; nanocarriers; solubility; stability; bioefficacy; vesicles; cochleates; polymeric nanoparticles; brain delivery; skin delivery
Interests: natural products; nanocarriers; stealth and cationic liposomes; microemulsions; nanoemulsions; oral administration
Natural products have a wide range of applications with a profound impact in the medical and healthcare fields. In the last decade, numerous delivery systems based on natural products have been developed to optimise their biopharmaceutical properties, to achieve desirable target characteristics, to reduce doses and side effects, and even to achieve therapeutic levels of drugs over an extended period.
This is generally related to the scarce water solubility, low lipophilicity and inappropriate molecular size of natural compounds, which undergo structural instability in a biological milieu, rapid clearance and a high metabolic rate. Additionally, some molecules are destroyed in gastric juice or suffer a massive pre-systemic metabolism in the liver when administered orally, limiting their clinical use. Reduced bioavailability can be also linked to drug distribution/accumulation in non-targeted tissues and organs that increase the side effects, lowering the therapeutic efficacy and patient compliance. Delivery systems represent favourable tools to increase the bioavailability and activities of natural products.
Dr. Anna Rita Bilia
Dr. Maria Camilla Bergonzi
Dr. Vieri Piazzini
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Natural products
- Delivery systems
- Polymeric carriers
- Lipid carriers