Rat Lungworm Disease
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 24547
Special Issue Editor
Interests: neuroangiostrongyliasis; rat lungworm disease; Angiostrongylus cantonensis; infectious disease; neuroimmunology; avian malaria (Plasmodium relictum); avipoxvirus
Special Issue Information
Dear Colleagues,
The parasitic nematode Angiostrongylus cantonensis is a global causative agent of eosinophilic meningitis in humans. It is sometimes referred to as neuroangiostrongyliasis or colloquially known as rat lungworm disease. This disease has resulted in morbidity and mortality in humans and other accidental hosts, and the geographical range of this parasite continues to increase through global expansion. The parasites’ life cycle involves development to the adult stage in the pulmonary vasculature of the definitive rat host, which then produces thousands of eggs from which first stage larvae (L1) develop. L1s are subsequently released in the rat feces. Slugs and snails consume L1 in rat feces, and essential intermediate development continues to the L3 infective stage. Accidental hosts ingest the L3 either in food, water, or other beverages and become infected. Humans are not the only vertebrate species affected; others include non-human primates, dogs, fruit bats, horses, marsupials, some species of birds, and many more. In this Special Issue, we proudly showcase the valuable research work providing the most current and fascinating information available on A. cantonensis and the infections they can cause. This collective body of literature greatly advances our critical knowledge of A. cantonensis and this disease.
Prof. Dr. Susan Jarvi
Guest Editor
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Keywords
- Angiostrongylus cantonensis
- rat lungworm
- neuroangiostrongyliasis
- accidental hosts
- parasitic nematode
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