Special Issue "Prions and Prion-like Transmissible Protein Pathogens"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (31 May 2020).
Interests: Parkinson’s disease, prion disease, protein aggregation in neurodegenerative diseases, prions, pathogenesis of neurodegenerative
Prions are infectious proteins that are associated with a group of transmissible neurodegenerative diseases in humans and animals, such as Creutzfeldt–Jakob disease in humans, scrapie in sheep and goats, mad cow disease in cattle, and chronic wasting disease in elk and deer. Unlike traditional pathogens such as bacteria and viruses that always require genetic material DNA for their propagation, the infectious prion proteins are able to propagate and duplicate and spread from individual to individual in the absence of DNA. Interestingly, prion-like proteins have also recently been observed in other neurodegenerative diseases, such as Alzheimer disease, Parkinson’s disease, amyotrophic lateral sclerosis, etc. These share the prion-like features of propagation and transmission from cell to cell, although in contrast to prions, transmission from individual to individual has not be reported in these prion-like misfolded proteins. Now, prions have become the prototypes for these emerging groups of transmissible protein pathogens.
The annual international Prion conference will take place from May 21–24, 2019 in Edmonton, Alberta, Canada. This Special Issue welcomes prion researchers and experts who wish to highlight new developments in prions and prion-like transmissible misfolded protein pathogens that emerge in the conference. In addition, we shall also accept original research and review articles about pathogenesis, diagnosis, and potential therapeutic responses to human and animal prion diseases. We especially seek manuscripts that report emerging atypical prions and prion diseases as well as innovative strategies and methods for the determination of prions and treatment of prion diseases.
We look forward to your contributions and to a valuable Special Edition that will promote further developments in this exciting field.
Dr. Wenquan Zou
Prof. Jiyan Ma
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Prion diseases
- Prion 2019 conference
- Neurodegenerative disorders
- Protein misfolding disorders
- Protein aggregations
- Alzheimer’s disease
- Parkinson’s disease