Special Issue "Factors Influencing the Colonization and Pathogenesis of Candida albicans in the Gut"
Deadline for manuscript submissions: 31 December 2021.
Candida albicans, an opportunistic fungal pathogen present in the gastrointestinal (GI) of humans, is harmless to immunocompetent hosts with intact gut microbiota. However, administration of antibiotics and chemotherapeutic agents increases the risk of C. albicans infections by increasing the frequency and magnitude of GI colonization by C. albicans, and the source of systemic infection is often confirmed to be the GI tract. This new Special Issue of Pathogens will explore topics related to colonization and pathogenesis of C. albicans in the gut. We welcome submissions on all aspects of C. albicans related to commensalism, morphogenesis, virulence, pathogenesis, and treatment strategies within the context of the GI tract. We invite you to submit research and review articles related to these topics, and we look forward to your contribution.
Dr. Shankar Thangamani
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
In vitro exploration of probiotic interactions with Candida using novel methods to model dysbiotic conditions in colonized tissues
Authors: Emma Whittman OMSII, Neela Yar OMSII, Francesco De Seta MD and Bryan Larsen PhD
Abstract: Gut dysbiosis involving Candida albicans is receiving significant interest by clinicians and researchers and is being informed significantly by the microbiome studies which have been done in the last decade. For a longer period of time, however, our laboratory has been interested in dybiosis of the lower female genital tract and the mechanisms involved with apparently commensal organisms that may at time generate symptoms. Having developed methods exploiting flow cytometry as a means of in vitro investigation of interactions between endogenous yeast and probiotic organisms we show how the interaction between probiotic bacteria and Candida interact and how the interactions can be influenced by enhancing and inhibiting substances present in pharmaceutical preparations. We will explore as background the interaction between probiotic organisms and organisms associated with vaginal symptoms and consider how these interactions and methods used to explore them, may be informative in the study of gut dysbiosis involving fungal species.