Pathogenesis and Treatment of Non-Tuberculous Mycobacterial Infections
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: 15 May 2025 | Viewed by 1961
Special Issue Editors
Interests: mycobacterial diseases; pathogenesis; innate immunity; immunometabolism
Special Issues, Collections and Topics in MDPI journals
Interests: mycobacterial infections; tuberculosis treatment; infections; resistant TB
Special Issue Information
Dear Colleagues,
Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause significant disease in both immunocompromised and immunocompetent individuals. The incidence of NTM pulmonary disease (NTM-PD) is rising globally. However, the efficiency of treatment is variable. Common causative organisms of pulmonary infection are slowly growing mycobacteria, including the Mycobacterium avium complex and Mycobacterium kansasii, and rapidly growing mycobacteria, including the Mycobacterium abscessus complex. Future approaches to the management of NTM pulmonary disease will require specific therapies that are well tolerated; can be taken for a shorter time and, perhaps, less frequently; have few drug–drug interactions; and are active against the various strains of pathogens. There is a demand for drugs that specifically target these bacteria, but we cannot exclude the possibility of using a host-direct therapy strategy. As the number of infections increases, such therapies will be welcomed by clinicians and patients.
In this Special Issue, we aim to provide a collection of research articles, comprehensive reviews, and short communications in line with the treatment and pathogenesis of NTM infections. Through this collection, we will pinpoint the current situation and future perspectives of the control of pulmonary disease caused by NTM.
We look forward to your involvement in this Special Issue.
Prof. Dr. Roberta Olmo Pinheiro
Prof. Dr. Margareth Pretti Dalcolmo
Dr. Ana Carolina Carvalho
Guest Editors
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Keywords
- non-tuberculous mycobacteria
- treatment
- pathogenesis
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