Prebiotics and Probiotics in Metabolism Disorder

Dear Colleagues,

Microbial community structural and functional disorder (dysbiosis) has been linked to numerous diseases, including diabetes mellitus, obesity, cardiovascular disease, gastrointestinal disorders, mental disease, and cancer. The use of prebiotics or probiotic bacteria is a promising way to achieve disease prevention and treatment. The introduced probiotic strains pass through the digestive tract or accumulate at a specific site in the intestine, producing numerous metabolites, inhibiting pathogen colonization, regulating immunity, and together with prebiotics, positively modulating the balance of gut bacterial composition and its metabolites, thus, exerting beneficial effects. Through prebiotics or probiotic supplementation for preventing the disruption of microbial communities, they represent an alternative health regulation strategy. Studies have revealed, especially, that the consumption of prebiotics and probiotic supplementation, and the resulting improvement in gut microbiota dysbiosis, significantly improve the overall health of patients with diabetes and metabolic diseases. This Special Issue covers all aspects of using prebiotics and probiotics to treat diabetes and metabolism disorder in humans and model organisms (mammals, other vertebrates, and invertebrates). The goal of this Special Issue is to provide a platform for all researchers to better understand the importance of prebiotics and probiotics as therapeutic strategies for diabetes and metabolism disorder.

Kind regards,

Dr. Gang Wang
Guest Editor

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