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Magnesium in Aging, Health and Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 9

Special Issue Editors


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Guest Editor
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90100 Palermo, Italy
Interests: aging; health; diseases; nutrition; magnesium
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Medicine, Kore University of Enna, 94100 Enna, Italy
Interests: aging; health; diseases; nutrition; magnesium

Special Issue Information

Dear Colleagues,

Magnesium (Mg) metabolism undergoes several changes with aging, including reduced dietary intake, impaired intestinal absorption, and increased renal excretion. Mild Mg deficiency is often asymptomatic, with vague or absent clinical signs, making it easily overlooked. However, chronic Mg deficiency promotes oxidative stress by increasing free radical production, contributing to the development of various age-related diseases.

Low Mg levels have been linked to a wide range of conditions, including cardiovascular diseases, hypertension, stroke, metabolic syndrome, type 2 diabetes, respiratory disorders such as asthma, depression, psychiatric conditions, Alzheimer’s disease, other dementias, chronic fatigue, fibromyalgia, bone fragility, and cancer.

Given its widespread physiological roles and potential impact on aging-related pathologies, Mg status deserves careful attention, particularly in older adults. Dietary Mg intake and/or supplementation—including Mg-rich water sources—should be considered in the prevention or correction of Mg deficits.

In this Special Issue, we welcome original research, reviews, and meta-analyses encompassing in vitro, animal, and human in vivo studies. Submissions addressing genetic, epigenetic, and metabolic aspects of Mg, as well as public health strategies for Mg fortification, are strongly encouraged. Our goal is to advance the understanding of how Mg may contribute to health optimization.

Prof. Dr. Mario Barbagallo
Prof. Dr. Ligia J. Domínguez
Prof. Dr. Nicola Veronese
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • magnesium
  • health
  • nutrition
  • diabetes
  • hypertension

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Published Papers

This special issue is now open for submission.
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