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Dietary Bioactive Compounds: Implications for Oxidative Stress and Inflammation–2nd Edition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: closed (25 February 2024) | Viewed by 746

Special Issue Editors


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Guest Editor
1. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy
2. Interdepartmental Research Center “Nutraceuticals and Food for Health”, University of Pisa, 56100 Pisa, Italy
Interests: phenolic compounds; polyphenols; neuroprotection; antioxidant; nutraceutical; olive oil; medicinal chemistry; analytical chemistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy
2. Interdepartmental Research Center “Nutraceuticals and Food for Health”, University of Pisa, 56100 Pisa, Italy
Interests: phytochemicals; polyphenols; nutraceuticals; bioactives; food waiste; olive oil; medicinal chemistry; synthetic chemistry; analytical chemistry; biological screening
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The regular consumption of fruits and vegetables has preventative effects against various chronic diseases that are closely associated with oxidative stress and inflammation due to the presence of bioactive compounds. Dietary bioactives, particularly phytochemicals such as polyphenols, flavonoids, vitamins, and fibers, are recognized for their beneficial health properties, including their anti-inflammatory and antioxidant activities. Therefore, bioactives appear to be novel candidates for both pharmaceutical and nutraceutical applications. Nevertheless, some pharmacokinetic drawbacks, including reduced intestinal absorption, low bioavailability, and rapid metabolic modifications, should be assessed to exploit their therapeutical properties.

Considering the success of the previous Special Issue, “Dietary Bioactive Compounds: Implications for Oxidative Stress and Inflammation", we are pleased to announce that we are launching a second edition Special Issue on this topic.  This Special Issue on “Dietary Bioactive Compounds: Implications for Oxidative Stress and Inflammation: 2nd Edition” will continue to collect and discuss the recent developments in research regarding all of the aspects of bioactive compounds that are involved in various diseases, mediated by inflammatory and oxidative processes. More specifically,  original papers should focus on the implication of dietary bioactive compounds in different molecular pathways and propose modern cell and molecular biology methodologies. Furthermore, considering bioavailability as a key element to ensure the bio-efficacy of these compounds, studies on the absorption and metabolism of dietary bioactive compounds are appreciated. This Special Issue will include both original scientific researches and systematic reviews.

Prof. Dr. Maria Digiacomo
Dr. Doretta Cuffaro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polyphenols
  • bioactive compounds
  • food
  • antioxidant
  • anti-inflammatory
  • bioavailability
  • health properties
  • oxidative stress
  • phytochemicals
  • nutraceutical

Published Papers (1 paper)

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Review

15 pages, 808 KiB  
Review
1-Acetoxypinoresinol, a Lignan from Olives: Insight into Its Characterization, Identification, and Nutraceutical Properties
by Ganesha Yanuar Arief Wijaya, Doretta Cuffaro, Simone Bertini, Maria Digiacomo and Marco Macchia
Nutrients 2024, 16(10), 1474; https://doi.org/10.3390/nu16101474 - 13 May 2024
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Abstract
Extra virgin olive oil (EVOO) is a symbol of the Mediterranean diet, constituting its primary source of fat. The beneficial effect of EVOO is strictly related to the presence of fatty acids and polyphenols, bioactive compounds endowed with nutraceutical properties. Among EVOO polyphenols, [...] Read more.
Extra virgin olive oil (EVOO) is a symbol of the Mediterranean diet, constituting its primary source of fat. The beneficial effect of EVOO is strictly related to the presence of fatty acids and polyphenols, bioactive compounds endowed with nutraceutical properties. Among EVOO polyphenols, lignans possess a steroid-like chemical structure and are part of the phytoestrogen family, which is renowned for its health properties. The natural lignans (+)-pinoresinol and 1-acetoxypinoresinol (1-AP) are commonly present in olives and in EVOO. Although (+)-pinoresinol is found in different edible plants, such as flaxseed, beans, whole-grain cereals, sesame seeds, and certain vegetables and fruit, 1-AP was exclusively identified in olives in 2000. So far, the scientific literature has extensively covered different aspects of (+)-pinoresinol, including its isolation and nutraceutical properties. In contrast, less is known about the olive lignan 1-AP. Therefore, this review aimed to comprehensively evaluate the more important aspects of 1-AP, collecting all the literature from 2016 to the present, exploring its distribution in different cultivars, analytical isolation and purification, and nutraceutical properties. Full article
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