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Food-Derived Bioactive Compounds and Their Health Benefits

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 15 December 2025 | Viewed by 40

Special Issue Editors

1. FP-BHS—Biomedical and Health Sciences Research Unit, FFP-I3ID Faculty of Health Sciences, University of Fernando Pessoa, 4200-150 Porto, Portugal
2. RISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia 296, 4200-150 Porto, Portugal
3. Associate Laboratory i4HB—Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
4. UCIBIO—Applied Molecular Biosciences Unit, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: bioactive compounds; bioactive skin delivery; nutraceuticals; clinical evidence-based healthcare; decision-making policy

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Guest Editor
1. FP-BHS—Biomedical and Health Sciences Research Unit, FFP-I3ID Faculty of Health Sciences, University of Fernando Pessoa, 4200-150 Porto, Portugal
2. RISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia 296, 4200-150 Porto, Portugal
Interests: nutritional epidemiology; community nutrition and public health; dietary patterns and health; evidence-based nutrition

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Guest Editor
1. FP-BHS—Biomedical and Health Sciences Research Unit, FP-I3ID—Instituto de Investigação, Inovação e Desenvolvimento, Faculty of Health Science, Fernando Pessoa University, 4200-150 Porto, Portugal
2. Associate Laboratory i4HB—Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
3. UCIBIO—Applied Molecular Biosciences Unit, MedTech—Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, 050-313 Porto, Portugal
4. RISE—Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia 296, 4200-150 Porto, Portugal
Interests: bioactive delivery systems; lipid-based nanosystems; hybrid nanosystems; controlled delivery; multifunctional nanosystems
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Special Issue Information

Dear Colleagues,

Food-derived bioactive compounds have garnered increasing scientific interest due to their significant potential to contribute in disease prevention and health promotion. Bioactive compounds, which occur naturally in a wide variety of foods, have a broad spectrum of biological activities, including antioxidant, anti-inflammatory, antihypertensive, lipid-lowering, and neuroprotective effects. Recent advances have also emphasized their role in modulating the gut microbiota, metabolic pathways, and immune responses.

Despite their promising biological activities, the clinical efficacy of these bioactive is often limited by challenges associated with their stability, metabolism, and, particularly, their bioavailability. As such, current research is increasingly focused on the development of innovative delivery systems and food matrix engineering strategies to enhance the bioaccessibility, absorption, and systemic activity of bioactive.

This Special Issue aims to gather high-quality contributions that address the latest discoveries on food-derived bioactive compounds, with a particular emphasis on their health benefits, mechanisms of action, and innovative approaches to improve their bioavailability. Clinical, experimental and in vitro studies, as well as reviews, and interdisciplinary studies are all welcome, especially those that bridge food science, nutrition, pharmacology, and health-related disciplines.

Dr. Rita Oliveira
Dr. Cláudia Silva
Dr. Carla Martins Lopes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutraceuticals
  • health-promoting compounds
  • bioactive compounds
  • bioavailability enhancement
  • delivery systems for bioactives
  • chronic disease prevention

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Published Papers

This special issue is now open for submission.
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