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Journals
Nanomaterials
Special Issues
Emerging Nanotechnologies for Smart and Functional Medical Implants
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Emerging Nanotechnologies for Smart and Functional Medical Implants

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (30 May 2026) | Viewed by 830

Editors

Dr. Csaba Balázsi

E-Mail Website
Guest Editor
Institute of Technical Physics and Materials Science, HUN-REN Centre for Energy Research, Konkoly-Thege, Miklós Str. 29-33, Budapest 1121, Hungary
Interests: bioceramics; biomaterials; ceramic dispersion strengthened steels; ceramics and nanocomposites for high temperature and tribological applications; open structured functional materials for sensorics; fiber polymers; composites and coatings; layered ceramics
Special Issues, Collections and Topics in MDPI journals
Dr. Katalin Balázsi

E-Mail Website
Guest Editor
Centre for Energy Research, Institute of Technical Physics and Materials Science, 1121 Budapest, Hungary
Interests: bioceramic; thin films; TEM; ceramic composite
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue provides an up-to-date overview of the present applications of nanotechnology-based biomaterials in orthopedic implants, bone regeneration, and bone tissue engineering and their prospective future applications in drug delivery systems or smart scaffold fabrication. Nanomaterials with tailored bioactivity, biocompatibility, or biodegrability have great potential for use in medical implant designs and orthopedic applications due to their exceptional functional properties and capability to maintain drug release and promote osseointegration and tissue regeneration. Moreover, nanotechnology-based biomaterials are able to mimic the features and hierarchical structure of native cortical or trabecular bones. They facilitate cell proliferation, decrease the rate of infection, and prevent biofilm formation, among other diverse functions. The emergence of nanostructured polymers, metals, ceramics, composites, and carbon materials has facilitated novel approaches in medical implant designs in orthopedic research. We welcome articles and review papers that provide concise insights into nanotechnology-based biomaterials that are utilized in orthopedics, covering metallic and nonmetallic nanomaterials.

Dr. Csaba Balázsi
Dr. Katalin Balázsi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology-based biomaterials
  • drug delivery systems
  • bioactive coatings
  • biocompatible nanocomposites
  • biodegradable materials
  • bone tissue engineering
  • novel scaffolds by additive manufacturing
  • surface modification of implants
  • bone regeneration

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Published Papers (1 paper)

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Research

21 pages, 22963 KB  
Article
Mechanical Versus Laser Debridement of SLA Titanium Implants: An In Vitro Morphological and Elemental Analysis of Debris Removal and Surface Preservation
by Baran Yurdakul, Sumeyye Meyvaci, Gokce Aykol-Sahin, Aslan Gokbuget, Funda Yalcin and Ulku Baser
Nanomaterials 2026, 16(12), 703; https://doi.org/10.3390/nano16120703 - 6 Jun 2026
Viewed by 437
Abstract
Peri-implantitis treatment is challenging because of the complex micro- and nanostructured topography of implant surfaces. No standard debridement protocol exists. In this study, we compared five debridement methods used on heavily contaminated titanium implants that were explanted due to peri-implantitis. Twenty-five explanted implants [...] Read more.
Peri-implantitis treatment is challenging because of the complex micro- and nanostructured topography of implant surfaces. No standard debridement protocol exists. In this study, we compared five debridement methods used on heavily contaminated titanium implants that were explanted due to peri-implantitis. Twenty-five explanted implants (five per group) were treated with a carbon fiber ultrasonic insert, a polyetheretherketone (PEEK) ultrasonic insert, a rotating titanium brush, an erbium, chromium-doped yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser, or an erbium-doped yttrium, aluminum, and garnet (Er:YAG) laser. Five pristine implants were used as controls. Surface morphology was assessed by scanning electron microscopy (SEM). The Modified-Implant Debridement Visual Index (M-IDVI) was used to assess the debridement effectiveness according to SEM images. Surface elemental composition was assessed for atomic percentage (at. %) of carbon, titanium, oxygen and nitrogen using energy-dispersive X-ray spectroscopy (EDS). Mechanical methods were more effective at removing debris than laser methods. The titanium brush showed the lowest residual debris (2.33 ± 0.33) and the greatest reduction in surface carbon (Δ = −7.77 at. %). Surface titanium increased after debridement for all methods except for Er,Cr:YSGG (Δ = −5.9 at. %). Er:YAG best preserved SLA microtopography but exhibited a lower debridement efficacy (3.27 ± 0.83) than mechanical methods. No method resulted in a pristine surface. Full article
(This article belongs to the Special Issue Emerging Nanotechnologies for Smart and Functional Medical Implants)
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