Special Issue "Vibrational Probes of Biomolecular Structure and Dynamics"
Deadline for manuscript submissions: 15 February 2019
Prof. Dr. Chong Fang
Department of Chemistry, 153 Gilbert Hall, Oregon State University, Corvallis, OR 97331, USA
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Interests: femtosecond Raman; vibrational probes; structural dynamics; fluorescent proteins; photoacids; photophysics and photochemistry; excited state processes; energy relaxation; proton transfer; hydrogen bonding interactions; nonlinear optics; ultrafast spectroscopy
The past few decades have seen tremendous progress in understanding the structure–function relationships of biomolecular systems from microscopic motions to macroscopic properties. Among all the molecular characterization methods, vibrational probes stand out as a versatile and fruitful endeavor because they are highly sensitive to local environment and can be designed, modified, positioned, and controlled to reveal previously unavailable, unknown, or unattainable information about the system under investigation.
The vibrational probes used for steady-state biomolecular structural determination include functional groups and chemical compounds such as carbonyl, nitrile, azide, and cyanamide, while the time-resolved studies can use those characteristic probes to track equilibrium processes (e.g., anharmonic coupling, H-bonding interactions, spectral diffusion, chemical exchange, energy transport) and non-equilibrium processes (e.g., protein folding and unfolding, cooling, electron and proton transfer, transient absorption, fluorescence). Such a wealth of information has been obtained by active researchers across the modern disciplines of physical chemistry and chemical physics, biophysics and biochemistry, ultrafast spectroscopy and nonlinear optics, chemical biology, imaging and microscopy. Individual or pairs of isotopically labeled, engineered or non-natural probes, in conjunction with various advanced spectroscopic and microscopic techniques based on light-matter interactions, have further expanded the repertoire of vibrational toolset.
The aim of this Special Issue is to bring together leading experts across disciplines and highlight recent advances utilizing vibrational probes to study biomolecular structure and dynamics. Both original research articles and reviews are welcome, and articles that report or propose new ideas and new directions to stimulate future development and applications are particularly welcome.
Prof. Dr. Chong Fang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access bimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- structure-function relationships
- molecular spectroscopy
- imaging and microscopy
- protein engineering
- bioprobe development
- potential energy surface
- vibrational dynamics
- functional motions and interactions
- equilibrium and non-equilibrium processes