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Special Issue "Natural Compound to Biocontrol Agrarian Pests"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 July 2019

Special Issue Editor

Guest Editor
Prof. Dr. Antonio Evidente

Department of Chemical Sciences, University of Naples “Federico II”, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy
Website | E-Mail
Interests: ecology; biological control; plant pathology plant physiology; organic chemistry; bioactive natural substances; natural product isolation and characterization; spectroscopy; biopolymer for formulation of natural products

Special Issue Information

Dear Colleagues,

Pests, including weedy and parasitic plants, microbial pathogens, insect, etc., are one of the most serious problems for agriculture, affecting the production of healthy harvest in sufficient amounts, as they also infests economically important crops causing marked losses in agrarian yield. Pests also generate significant ecological problems, in particular to forests, ornamental heritages, archaeological areas, and green-house pasture industries. Agrarian pests include pathogenic fungi and bacteria that infect the host plants frequently causing their death, weed and parasitic plants, such as Striga, Orobanche, Phelipanche, and Cuscuta, which are root parasitic plants that acquire nutrients and water from their host causing significant harm, and insects that seriously damage or completely eat their hosts. Several management strategies have been applied to control the agrarian production, including mechanical, cultural, chemical, and biological strategies, but they have not provided a satisfactory solution to plant pest diffusion. The massive use of chemicals, including fungicides, bacteriocides, herbicides, and insecticides, differing widely with respect to their spectrum of action, unit activity, crop safety, toxicology, and environmental effects, has increased pest resistance; in addition, environmental and toxicological concerns raise questions over their large-scale use. These problems urge to focus on developing alternative strategies based on the use of natural products, in particular, bacterial, fungal, and plant metabolites, alone as natural pesticides, or in combination with producers or allelopathic plants extracts or root exudates, for a more efficient, integrated management. The development of new, efficient, and safe formulations of natural pesticides is one of the most important objectives to be reached. The complexation of natural products with available or new biopolymers could also be a means to enhance the bioavailability of poorly soluble metabolites by increasing their solubility in water.

Prof. Dr. Antonio Evidente
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • safe pesticides (bacteriocides, fungicides, herbicides, insecticides)
  • source and chemical characterization
  • natural products
  • biological activities
  • chemical modification
  • formulation in biopolymers
  • integrated management

Published Papers (2 papers)

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Research

Open AccessArticle Insecticidal Activities of Chloramphenicol Derivatives Isolated from a Marine Alga-Derived Endophytic Fungus, Acremonium vitellinum, against the Cotton Bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)
Molecules 2018, 23(11), 2995; https://doi.org/10.3390/molecules23112995
Received: 27 September 2018 / Revised: 14 November 2018 / Accepted: 15 November 2018 / Published: 16 November 2018
PDF Full-text (1806 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A great deal of attention has been focused on the secondary metabolites produced by marine endophytic fungi, which can be better alternatives to chemicals, such as biopesticides, for control of polyphagous pests. On the basis of its novel biocontrol attributes, chemical investigation of
[...] Read more.
A great deal of attention has been focused on the secondary metabolites produced by marine endophytic fungi, which can be better alternatives to chemicals, such as biopesticides, for control of polyphagous pests. On the basis of its novel biocontrol attributes, chemical investigation of a marine alga-derived endophytic fungus, Acremonium vitellinum, resulted in the isolation of three chloramphenicol derivatives (compounds 13). Their chemical structures were elucidated by detailed analysis of their nuclear magnetic resonance spectra, high-resolution electrospray ionization mass spectrometry, and by comparison with the data available in the literature. In this paper, compound 2 was firstly reported as the natural origin of these fungal secondary metabolites. The insecticidal activities of compounds 13 against the cotton bollworm, Helicoverpa armigera, were evaluated. The natural compound 2 presented considerable activity against H. armigera, with an LC50 value of 0.56 ± 0.03 mg/mL (compared to matrine with an LC50 value of 0.24 ± 0.01 mg/mL). Transcriptome sequencing was used to evaluate the molecular mechanism of the insecticidal activities. The results presented in this study should be useful for developing compound 2 as a novel, ecofriendly and safe biopesticide. Full article
(This article belongs to the Special Issue Natural Compound to Biocontrol Agrarian Pests)
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Open AccessFeature PaperArticle Curvulin and Phaeosphaeride A from Paraphoma sp. VIZR 1.46 Isolated from Cirsium arvense as Potential Herbicides
Molecules 2018, 23(11), 2795; https://doi.org/10.3390/molecules23112795
Received: 8 October 2018 / Revised: 21 October 2018 / Accepted: 25 October 2018 / Published: 28 October 2018
PDF Full-text (2524 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Phoma-like fungi are known as producers of diverse spectrum of secondary metabolites, including phytotoxins. Our bioassays had shown that extracts of Paraphoma sp. VIZR 1.46, a pathogen of Cirsium arvense, are phytotoxic. In this study, two phytotoxically active metabolites were isolated
[...] Read more.
Phoma-like fungi are known as producers of diverse spectrum of secondary metabolites, including phytotoxins. Our bioassays had shown that extracts of Paraphoma sp. VIZR 1.46, a pathogen of Cirsium arvense, are phytotoxic. In this study, two phytotoxically active metabolites were isolated from Paraphoma sp. VIZR 1.46 liquid and solid cultures and identified as curvulin and phaeosphaeride A, respectively. The latter is reported also for the first time as a fungal phytotoxic product with potential herbicidal activity. Both metabolites were assayed for phytotoxic, antimicrobial and zootoxic activities. Curvulin and phaeosphaeride A were tested on weedy and agrarian plants, fungi, Gram-positive and Gram-negative bacteria, and on paramecia. Curvulin was shown to be weakly phytotoxic, while phaeosphaeride A caused severe necrotic lesions on all the tested plants. To evaluate phaeosphaeride A’s herbicidal efficacy, the phytotoxic activity of this compound in combination with five different adjuvants was studied. Hasten at 0.1% (v/v) was found to be the most potent and compatible adjuvant, and its combination with 0.5% (v/v) semi-purified extract of Paraphoma sp. VIZR 1.46 solid culture exhibited maximum damage to C. arvense plants. These findings may offer significant importance for further investigation of herbicidal potential of phaeosphaeride A and possibly in devising new herbicide of natural origin. Full article
(This article belongs to the Special Issue Natural Compound to Biocontrol Agrarian Pests)
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