Therapeutic Potential of Bioactive Compounds Against Neurodegenerative Diseases
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 243
Editors
Interests: organic synthesis; natural products; NMR characterization; biological assessments
Special Issues, Collections and Topics in MDPI journals
Interests: organic synthesis; medicinal chemistry; biological assessments; antiparasitic drug development; RNA-ligands; antibiotic development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis, represent a growing global health concern due to aging populations and the absence of effective disease-modifying therapies. These disorders are characterized by complex and interconnected pathological mechanisms, including oxidative stress, neuroinflammation, mitochondrial dysfunction, protein misfolding and aggregation, and progressive neuronal loss.
Throughout the years, bioactive compounds have attracted significant attention for their varying biological properties, in particular the prevention, treatment and modulation of these neurodegenerative diseases. Many of these molecules exhibit antioxidant, anti-inflammatory, and anti-apoptotic properties, as well as the ability to modulate signalling pathways associated with neuronal survival, synaptic plasticity, and cellular homeostasis, emerging as promising candidates for the treatment of this type of disease.
The following Special Issue, entitled “Therapeutic Potential of Bioactive Compounds Against Neurodegenerative Diseases,” gathers pioneering research and reviews showcasing recent advances in this area. Your research on discovery, mechanisms, and delivery strategies can inspire progress and highlight the critical role of interdisciplinary efforts in developing new treatments.
Dr. Diana Cláudia Gouveia Alves Pinto
Guest Editor
Dr. Carlos Fábio Magalhães da Silva
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- neurodegenerative diseases
- bioactive compounds
- drug discovery
- medicinal chemistry
- structure-activity relationship
- mechanisms of action
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