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Molecules Medicinal Chemistry Reviews, 2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Chemistry, Institute of Pharmacy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria
Interests: opioid receptors; opioid pharmacology; pain research; CNS disorders; opioid drug discovery; structure–activity relationships; GPCRs signaling
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
Interests: anticancer agents; molecular chaperones; small molecules; protein–protein interaction; computer-aided drug design
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, “Molecules Medicinal Chemistry Reviews, 2nd Edition”, aims to publish high-quality review articles that report the latest advances and challenges, and provide valuable perspectives in the field of medicinal chemistry. Medicinal chemistry continues to play a central role in drug discovery and development, bridging chemistry and biology to address urgent medical challenges and unmet therapeutic needs. Through this Special Issue, we aim to gather contributions from scientists that will inspire innovation and guide future research in medicinal chemistry. We welcome comprehensive review papers covering, but not limited to, advances in drug design and discovery, structure–activity relationships (SARs) and pharmacophore modeling, novel synthetic methodologies relevant to medicinal chemistry, emerging therapeutic targets and strategies, applications of computational chemistry and AI in drug development, pharmacokinetics, metabolism, and toxicity considerations.

Dr. Mariana Spetea
Prof. Dr. Lei Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug discovery
  • drug design
  • computer-aided drug design
  • synthesis
  • pharmacophore
  • targets
  • structure-activity relationships
  • therapeutics

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This special issue is now open for submission.
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