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From Functionalization to Medical Applications of Polymer Materials

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 1522

Editors


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Special Issue Information

Dear Colleagues,

In this Special Issue we intend to collect manuscripts (research papers and review papers) concerning synthesis and applications of polymers for applications in medicine, by means of drug delivery, tissue engineering, tissue regeneration, bio-imaging, bio-detection, medicinal chemistry, internal medicine, surgery materials, cardiology, oncology, dermatology, neurology, radiology, and anesthesiology—anything related to medicine. Manuscripts can also include functionalization of polymers for medical applications. We accept synthetic and natural polymers as well as proteins that can be considered biological polymers. We retain that polymers, due to their structure, which exhibit numerous repeating molecular units, can amplify the properties of single molecules if well designed. We hope to collect innovative and useful manuscripts to increase the quality of the journal Molecules.

Dr. Paolo Coghi
Dr. Carmine Coluccini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymer functionalization
  • medical applications
  • drug delivery
  • tissue engineering
  • theranostic medicine

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Published Papers (1 paper)

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Research

16 pages, 1090 KB  
Article
Dual-Action Sutures: Chlorhexidine and Dexamethasone for Infection Control and Inflammation Suppression
by Brisa Guadalupe Hernández-Ramírez, Giovanni Palomino-Vizcaino, Lilia Angélica Hurtado-Ayala, Jonathan Vincent Lopez-Baena, Hebrón Vazquez-Estudillo, Arturo Estolano-Cobián, Teresa G. Rodriguez-Tellez, Héctor Milla-Hinojosa, José Manuel Cornejo-Bravo, Kenia Palomino-Vizcaino and Héctor Magaña
Molecules 2026, 31(7), 1200; https://doi.org/10.3390/molecules31071200 - 4 Apr 2026
Viewed by 1174
Abstract
Surgical site infections (SSIs) remain a major clinical challenge, particularly due to bacterial adhesion and biofilm formation on suture materials. In this study, we developed a dual drug-eluting suture incorporating chlorhexidine (CHX) and dexamethasone (DEX), with lauric acid used as a binding agent [...] Read more.
Surgical site infections (SSIs) remain a major clinical challenge, particularly due to bacterial adhesion and biofilm formation on suture materials. In this study, we developed a dual drug-eluting suture incorporating chlorhexidine (CHX) and dexamethasone (DEX), with lauric acid used as a binding agent to enhance drug adhesion. The exact composition of the system was CHX/DEX/Lauric Acid, designed to enable localized delivery of both therapeutic agents at the implantation site. Vicryl sutures were dip-coated and characterized by means of FTIR-ATR and HPLC to confirm drug incorporation and release. Mechanical integrity was preserved, with no significant difference in tensile strength between coated and uncoated sutures. Antimicrobial activity was confirmed against Gram-positive and -negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), in addition to the yeast Candida albicans. Cell viability assays demonstrated acceptable biocompatibility, with values exceeding 70%. These findings support the potential of dual-functionalized sutures to reduce SSIs and modulate inflammation, offering a promising strategy for improving postoperative outcomes. Full article
(This article belongs to the Special Issue From Functionalization to Medical Applications of Polymer Materials)
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