Nature-Inspired Antitumor Agents, 2nd Edition
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 2489
Special Issue Editor
Interests: medicinal chemistry; organic synthesis; drug discovery; anticancer activity; antimicrobial activity; chiral drugs; natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Medicinal chemistry in the twenty-first century has undergone innovative developments due to revolutions in biotechnology and informatics. These advances are mainly within the lead optimization process, but a very significant portion of these leads will continue to contain molecules which originate from natural products (NPs). The diversity of species from terrestrial plants, animals, microorganisms, and marine organisms results in a multitude of secondary metabolites with novel chemical structures and innovative mechanisms of action.
This renaissance of NPs is most allied with total synthesis, semi-synthesis, and analogue-based design. Nevertheless, other biotechnology and cheminformatics approaches are being used to investigate leads from nature. Among the activities of NPs, antitumor activity stands out. NPs like doxorubicin and taxol have their place in chemotherapy alongside new immunotherapies.
This Special Issue focuses on recent breakthroughs, which will help develop new antitumor agents inspired by the variety of NPs emerging as chemotherapeutics, and which intends to collect the state of the art with original research and review articles that consider NP analogues as potential antitumor drug candidates. Unique topics are welcomed.
Dr. Honorina Cidade
Guest Editor
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Keywords
- natural products
- antitumor activity
- NPs analogues-based design
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Related Special Issue
- Nature-Inspired Antitumor Agents in Molecules (9 articles)
