Special Issue "Synthesis of Flavonoids or Other Nature-Inspired Small Molecules"
Deadline for manuscript submissions: 31 December 2020.
Interests: medicinal chemistry; organic synthesis; analytical chemistry; mass spectrometry; NMR; natural products; molecular modeling
Every organic chemist should agree that, as stated by Nobel Laureate Frances H. Arnold, “by far, nature is the best chemist of all time”. Natural compounds are characterized by a unique variety of chemical structures, functional groups, and stereochemical properties. Moreover, from the medicinal chemistry point of view, several naturally occurring small molecules are endowed with valuable biological activities and have inspired the design and development of drugs.
Flavonoids represent an outstanding example among natural compounds. These molecules are polyphenols produced by plants and fungi, constituted by two phenyls and a heterocyclic ring, disposed differently according to the sub-category. Flavonoids and semi-synthetic derivatives have been extensively studied in light of their wide bioactivity spectrum: antioxidant, antiproliferative, antibacterial and anti-inflammatory. In addition, several other classes of natural or nature-inspired molecules, such as alkaloids and terpenoids, are particularly attractive from a chemical or biological perspective.
This Special Issue aims at collating original contributions describing the synthesis of natural compounds and semi-synthetic derivatives of natural molecules. Articles should contain original and efficient synthetic approaches or significant process innovations in the preparation of natural and semi-synthetic compounds, with a particular focus on biologically relevant molecules. Moreover, research articles reporting significant results concerning extraction procedures, structural elucidation and structural characterization of natural compounds and derivatives involving the use of advanced analytical techniques (chromatography, 1D and 2D NMR, mass spectrometry, IR and UV spectroscopy) are particularly welcome.
Dr. Giovanni Ribaudo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molbank is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- natural compounds
- semi-synthetic compounds
- organic chemistry
- structural elucidation
- analytical chemistry