CRISPR-Cas Microsystems in Diagnostics and Therapeutics: Innovations in Biosensor and Microfluidics
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B1: Biosensors".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 55
Special Issue Editors
Interests: CRISPR; microfluidic systems; pathogen detection; secondary metabolites; tissue culture
Special Issue Information
Dear Colleagues,
CRISPR-Cas systems have emerged as powerful and efficient tools for precise genome editing and transcriptional regulation across a wide range of organisms. Their simplicity, programmability, and versatility have positioned them at the forefront of modern biotechnology, enabling transformative applications in agricultural enhancement, therapeutic development, microbial engineering, and sustainable bioenergy production. CRISPR-based technologies are now routinely employed to investigate the molecular mechanisms underlying infectious, degenerative, and hereditary diseases, to improve crop yield and resilience, and to promote environmentally sustainable biofuel generation.
As CRISPR-Cas systems continue to evolve, advancements in their specificity, temporal control, and safety profiles are accelerating the translation of CRISPR-based interventions from the laboratory into clinical and field applications, with profound potential to impact global health and sustainability.
Given the rapid pace of innovation in this field, the continuous evaluation of technological progress and its broader implications is crucial. This Special Issue aims to showcase recent advances in CRISPR-Cas genome editing systems and explore the ethical dimensions surrounding the responsible deployment of these powerful tools.
We invite you to submit original research articles, review papers, and perspective pieces that contribute to the advancement of knowledge in the following areas:
- The detection of pathogens using CRISPR-Cas systems;
- CRISPR-enabled miniaturized biosensors for advanced diagnostics and therapeutics;
- Applications of CRISPR in microfluidic cell culture for drug discovery and tissue engineering;
- Exploring CRISPR-based approaches in biosensors for environmental, food, and health monitoring.
We look forward to receiving your contributions.
Dr. Ali Parsaeimehr
Dr. Ananda Nanjundaswamy
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- CRISPR-based diagnostics
- miniaturized biosensors
- microfluidic systems
- pathogen detection
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