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Medical Sciences
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Zinc: Its Molecular and Biochemical Importance, and Relevance in Medicine
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Zinc: Its Molecular and Biochemical Importance, and Relevance in Medicine

A special issue of Medical Sciences (ISSN 2076-3271).

Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 4263

Special Issue Editor

Dr. Arthur Grider

E-Mail Website
Guest Editor
Department of Foods and Nutrition, University of Georgia, Athens, USA

Special Issue Information

Dear Colleagues,

Zinc, as an essential trace element, is an important factor in numerous molecular and cellular pathways. The identification of zinc-dependent enzymes, zinc-binding proteins, and SLC30 and SLC39 zinc transporter families added significantly to our understanding of the magnitude of importance of zinc in cellular function. Zinc is essential for numerous metabolic functions, including insulin synthesis and signaling, glucose regulation, immune function, cognition, growth and development. This Special Issue is devoted to furthering our understanding of the roles zinc plays in cellular biochemical and physiological processes, as well as in pathological conditions. Topics to be covered in this Special Issue include, though not exclusively: immune function, acrodermatitis enteropathica, cancer, gut health and diarrhea, inflammation, oxidative stress, diabetes and glucose regulation, and bone health.  

Dr. Arthur Grider
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medical Sciences is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Acrodermatits enteropathica

  • Bone
  • Cancer
  • Diabetes
  • Diarrhea
  • Growth
  • Immune function
  • Zinc transporters

Published Papers (1 paper)

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Review

8 pages, 408 KiB  
Review
Zinc and Traumatic Brain Injury: From Chelation to Supplementation
by Cathy W. Levenson
Med. Sci. 2020, 8(3), 36; https://doi.org/10.3390/medsci8030036 - 17 Aug 2020
Cited by 14 | Viewed by 3952
Abstract
With a worldwide incidence rate of almost 70 million annually, traumatic brain injury (TBI) is a frequent cause of both disability and death. Our modern understanding of the zinc-regulated neurochemical, cellular, and molecular mechanisms associated with TBI is the result of a continuum [...] Read more.
With a worldwide incidence rate of almost 70 million annually, traumatic brain injury (TBI) is a frequent cause of both disability and death. Our modern understanding of the zinc-regulated neurochemical, cellular, and molecular mechanisms associated with TBI is the result of a continuum of research spanning more than three decades. This review describes the evolution of the field beginning with the initial landmark work on the toxicity of excess neuronal zinc accumulation after injury. It further shows how the field has expanded and shifted to include examination of the cellular pools of zinc after TBI, identification of the role of zinc in TBI-regulated gene expression and neurogenesis, and the use of zinc to prevent cognitive and behavioral deficits associated with brain injury. Full article
(This article belongs to the Special Issue Zinc: Its Molecular and Biochemical Importance, and Relevance in Medicine)
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