Special Issue "Treatments and Clinical Management of Menopausal Symptoms: Current Approaches and Future Perspectives"
Deadline for manuscript submissions: closed (31 December 2019).
Interests: women’s health; minimally invasive procedures; up-to-date management; gynecology; reproductive health; surgery
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Interests: gynecology; psychology; psychotherapy; quality of life; sexuality; sexual dysfunctions; menopause
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Menopause is defined as the point in time when menstrual cycles permanently cease because of the natural depletion of ovarian oocytes from aging. These elements reflect important changes in hormonal and metabolic homeostasis: in particular, low estrogen can result in vasomotor instability (such as hot flushes and night sweats), psychological changes (such as mood swings, depression, and difficulty concentrating), insomnia, genital tract atrophy (such as vaginal dryness, painful intercourse, and urinary incontinence), skin changes (such as thinning and decreased elasticity). In addition, lower androgen levels (male hormones) can contribute to the loss of sex drive.
Menopausal symptoms have a negative impact on quality of life, social relationships, and sexual activity. More specifically, the sexual sphere is particularly affected by the clinical manifestations of menopause, and it is common to observe menopausal women suffering from female sexual dysfunctions. The risk of sexual dysfunction for menopausal women grows with the decrease in estrogen levels and the ageing process. Women usually report diminished vaginal lubrication, pain and discomfort during intercourse, decreased arousal, and difficulty in achieving orgasm. Therefore, a multidisciplinary approach is needed in order to improve the clinical management of menopause.
The first line of treatment for menopausal symptoms includes non-hormonal vaginal lubricants, moisturizers, and regular sexual function. For women with moderate to severe vulvovaginal symptoms who do not benefit from the use of lubricants and moisturizers, estrogen therapy (topic or systemic) is generally recommended as a therapeutic standard. However, not all women want to use hormonal therapy, preferring treatments with nutraceuticals which have been shown to have positive effects in the treatment of menopausal disorders. Indeed, it has been underlined that selected nutrients and nutraceuticals may significantly ameliorate the symptoms and signs of menopause. On one hand, these compounds improve the quality of life, whereas on the other hand, they may also increase life expectancy by modifying known risk factors for comorbidities.
Considering these elements, this Special Issue aims to publish updated and groundbreaking original researches as well as comprehensive reviews about clinical management and treatment options for menopausal symptoms. Space will also be given to multidisciplinary contributions in order to better understand the impact of the different treatments on sexual function, couple relationship, and psychological wellbeing.
Potential topics include but are not limited to the following:
- Menopause and vulvovaginal atrophy symptoms
- Topical treatments for menopausal symptoms
- Systemic treatments for menopausal symptoms
- Nutrition and symptoms/signs of menopause
- The role of nutraceuticals during menopause
- Menopause and sexual dysfunctions
- Menopause and psycological symptoms
- Treatments of menopausal symptoms and quality of life
Dr. Antonio Simone Laganà
Dr. Valentina Lucia La Rosa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Menopausal symptoms
- Genitourinary syndrome of menopause
- Non-hormonal treatments
- Hormone therapy
- Vulvovaginal atrophy
- Quality of life