DPP-4 Inhibitors: Navigating the Intersection of Heart Health, Kidney Function, and Diabetes Management
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 3831
Special Issue Editor
Interests: heart failure; atrial fibrillation; ischemic cardiopathy; hospital administration; cardiovascular risk; lipidology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue titled "DPP-4 Inhibitors: Navigating the Intersection of Heart Health, Kidney Function, and Diabetes Management" focuses on the multifaceted role of Dipeptidyl Peptidase-4 (DPP-4) inhibitors in treating not only diabetes but also heart failure and kidney insufficiency. Originally designed to manage blood glucose levels in patients with type 2 diabetes, DPP-4 inhibitors have gained attention for their potential benefits in non-diabetic populations, particularly those with cardiovascular and renal conditions.
This Issue will explore the broader implications of DPP-4 inhibitors beyond glycemic control, examining their effects on heart and kidney health. Recent studies have shown that these drugs may help reduce the risk of heart failure and slow the progression of chronic kidney disease, even in non-diabetic patients. The Special Issue aims to highlight these emerging roles and discuss the mechanisms by which DPP-4 inhibitors exert protective effects on cardiovascular and renal systems, such as through anti-inflammatory and endothelial-regulating pathways.
Key topics include the use of DPP-4 inhibitors in heart failure management, where they have shown promise in reducing hospitalizations and improving heart function. Additionally, the Issue will cover their role in kidney insufficiency, focusing on how these agents can help delay the progression of diabetic and non-diabetic nephropathy. This comprehensive review will provide healthcare professionals with a deeper understanding of how to utilize DPP-4 inhibitors in a variety of clinical settings, enhancing treatment strategies for patients with or without diabetes who are at risk for cardiovascular and renal complications.
Dr. Francisco Epelde
Guest Editor
Manuscript Submission Information
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Keywords
- DPP-4 inhibitors
- heart failure
- kidney insufficiency
- cardiovascular health
- diabetes management
- non-diabetic patients
- endothelial regulation
- inflammation modulation
- chronic kidney disease
- nephropathy
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