Cancer Treatment: Clinical Applications of Cell Cultures
Deadline for manuscript submissions: closed (15 August 2021) | Viewed by 9614
Interests: cancer research; anticancer drug development; mouse models of cancer; xenografts; cell culture; natural products; small molecules
Special Issues, Collections and Topics in MDPI journals
Since their development at the end of the 19th/beginning of the 20th century, cell cultures have been the preferred technique for research in almost every biomedical field. Cell cultures involve cell isolation from their primary (natural) environment (from animals and/or patients) and the subsequent adaptation of these cells to grow in a controlled artificial environment (in vitro growth). One of the major advantages of this method is that cell cultures, to a great extent, keep the features of the natural environment (tissue and disease) from which they have been derived. Cells from specific living tissues, whether normal or diseased, can be cultured either as short-term or longer-term cultures (e.g., established cell lines). It is well known that the great advances and progress in biomedicine could not have been achieved without the use of cultured cells. However, it is not only research that has benefitted from cell cultures: diagnosis and the development of new therapies for deadly human diseases have been based on the use of cell cultures. Regenerative medicine, in vitro fertilization, and even precision medicine in cancer and current cancer immunotherapies are some clinical fields that have been advanced based on cell culture techniques saving and/or largely improving the quality of life of innumerous patients. In this context, this Special Issue of Medicina is dedicated to clinical applications of cell cultures for the treatment of cancer. We aim to host a unique collection of papers that will provide researchers with cutting-edge research and critical information on the potential role of cell cultures in the war against cancer.
Dr. Konstantinos Dimas
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- Precision medicine
- Primary cells
- Patient-derived cells
- Cancer stem cells