Mathematical Modeling and Computation in Systems Biology

Dear Colleagues,

Biological systems are inherently complex, encompassing multiple levels of biological functions—from molecular and cellular to ecological. Recent advances in high-throughput technologies have created a growing demand for systems biology to develop more precise models than can capture the intricate functions of genetic systems. However, the large number of interactions and competing processes often makes it difficult to grasp the full picture at once. Mathematical modeling provides a precise language describing and analyzing such complexity.

The purpose of this Special Issue is to present recent advances in mathematical and computational modeling in systems biology, with a particular focus on the formulation and analysis of dynamical models for complex biological systems at the cellular or molecular levels. We invite submissions of original research articles and reviews addressing quantitative aspects of modeling and computation in systems biology, including but are not limited to ordinary differential equations, delay-differential equations, fractional differential equations, and machine learning.

Prof. Dr. Xiong You
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Mathematics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.