Progress and Challenges in Emerging Therapies for Alzheimer’s Disease and Its Comorbidities
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 1006
Special Issue Editor
Interests: neuroscience; Alzheimer’s disease; in vivo studies; drug development; cannabinoid-based pharmaceuticals; repurposing current therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease remains one of the most pressing public health challenges worldwide, with its incidence increasing alongside aging populations. Despite significant progress in understanding its pathophysiology, truly effective therapies remain limited. In recent years, numerous emerging therapeutic strategies—ranging from novel pharmacological agents and immunotherapies to lifestyle-based and digital interventions—have shown promise. However, translation to clinical treatment is often hampered by the frequent presence of comorbidities such as cardiovascular, metabolic and neuropsychiatric conditions, which complicate treatment responses and the design of trials.
This Special Issue aims to present cutting-edge research and critical reviews on innovative therapeutic approaches to Alzheimer’s disease and its major comorbidities. We welcome original research, systematic reviews and meta-analyses that provide mechanistic insights, clinical trial results, personalized medicine approaches and integrative strategies that consider comorbid conditions. By assembling diverse contributions, this Special Issue seeks to highlight current progress, identify remaining challenges and foster interdisciplinary dialogue to accelerate the development of effective interventions for patients affected by Alzheimer’s disease in real-world, multimorbid contexts.
Dr. Gabriela Dumitrița Stanciu
Guest Editor
Manuscript Submission Information
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Keywords
- Alzheimer’s disease
- emerging therapies/novel treatments
- multimorbidity/comorbidities
- translational research
- cognitive decline
- drug development
- innovative approaches
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