Progress and Challenges in Emerging Therapies for Alzheimer’s Disease and Its Comorbidities
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 22 May 2026 | Viewed by 52
Special Issue Editor
Interests: neuroscience; Alzheimer’s disease; in vivo studies; drug development; cannabinoid-based pharmaceuticals; repurposing current therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease remains one of the most pressing public health challenges worldwide, with its incidence increasing alongside aging populations. Despite significant progress in understanding its pathophysiology, truly effective therapies remain limited. In recent years, numerous emerging therapeutic strategies—ranging from novel pharmacological agents and immunotherapies to lifestyle-based and digital interventions—have shown promise. However, translation to clinical treatment is often hampered by the frequent presence of comorbidities such as cardiovascular, metabolic and neuropsychiatric conditions, which complicate treatment responses and the design of trials.
This Special Issue aims to present cutting-edge research and critical reviews on innovative therapeutic approaches to Alzheimer’s disease and its major comorbidities. We welcome original research, systematic reviews and meta-analyses that provide mechanistic insights, clinical trial results, personalized medicine approaches and integrative strategies that consider comorbid conditions. By assembling diverse contributions, this Special Issue seeks to highlight current progress, identify remaining challenges and foster interdisciplinary dialogue to accelerate the development of effective interventions for patients affected by Alzheimer’s disease in real-world, multimorbid contexts.
Dr. Gabriela Dumitrița Stanciu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Alzheimer’s disease
- emerging therapies/novel treatments
- multimorbidity/comorbidities
- translational research
- cognitive decline
- drug development
- innovative approaches
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
