Role of Dentistry in the Precision Diagnosis and Therapy of Oral Cancer

Dear Colleagues,

Precision medicine is a customized approach to disease prevention and treatment. It also facilitates stratification of patient populations that vary in their susceptibility to disease and response to therapy. The recognition of tobacco, alcohol, and human papillomavirus as causative agents in oral and head and neck cancer has accelerated the development of diagnostic aids and treatment strategies to mitigate cancer progression. New “omics” technologies have revealed unique tumor biomarkers that have facilitated precision diagnosis and customized therapy. Recent advances in tumor immunology have stimulated renewed interest in the development of precision immunotherapy of oral and head and neck cancer. The future success of early diagnosis and tailored medical treatment for cancer patients will depend on discovering new druggable targets with improved therapeutic efficacy. As precision medicine becomes integrated into dental practice, and chair-side technologies are developed to facilitate early detection and risk assessment, patients’ long-term health outcomes with oral cancer will improve dramatically.

Prof. Dr. Peter Polverini
Guest Editor

Dr. Francesco Bennardo
Co-Guest Editor

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