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Special Issues
Personalized Dentistry: From Multidisciplinary Diagnosis to Precision Treatment
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Personalized Dentistry: From Multidisciplinary Diagnosis to Precision Treatment

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 20 February 2027 | Viewed by 1070

Editor

Dr. Giuseppe Lo Giudice

E-Mail Website
Guest Editor
Department of Clinical and Experimental Medicine, Messina University, 98100 Messina, Italy
Interests: restorative dentistry; endodontics; digital dentistry; sealers; biocompatibility; adhesion; CAD-CAM
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Personalized dentistry is an emerging field that integrates advances from various disciplines—such as genomics, digital imaging, biomaterials, and artificial intelligence—to revolutionize the diagnosis and treatment of dental pathologies.

As dental care evolves beyond traditional “one-size-fits-all” approaches, the importance of tailored treatment strategies is increasingly recognized for improving patient outcomes and quality of life.

Respecting the unique pathophysiological condition of each person requires a multidisciplinary approach to correctly evaluate and treat the interrelationships between systemic and oral diseases.

This Special Issue aims to gather innovative research and comprehensive reviews focused on the multidisciplinary aspects of personalized dentistry and medicine, highlighting how collaboration among different fields can enable precision in diagnosis and treatment planning.

We invite submissions of original research articles and reviews that align with the journal's scope:

  • Advanced diagnostic tools for personalized treatment planning;
  • Role of genetics and genomics in dental disease management;
  • AI and digital technologies for precision dentistry;
  • Ethical, educational, and regulatory perspectives on personalized care;
  • Integration of biomaterials in dental therapies;
  • Multidisciplinary case reports and treatment protocols in personalized dental medicine.

Dr. Giuseppe Lo Giudice
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • personalized dentistry
  • precision treatment
  • multidisciplinary diagnosis
  • digital dentistry
  • genomics
  • artificial intelligence
  • biomaterials
  • patient-specific therapy
  • clinical protocols
  • preventive dentistry

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 404 KB  
Article
Personalized Decision-Making in Periodontal Therapy: Systemic and Demographic Factors Influencing Surgical vs. Non-Surgical Re-Treatment
by Georgios S. Chatzopoulos and Larry F. Wolff
J. Pers. Med. 2026, 16(6), 290; https://doi.org/10.3390/jpm16060290 - 27 May 2026
Cited by 1 | Viewed by 653
Abstract
Background/Objectives: The aim of this retrospective cohort study was to identify and analyze the demographic, systemic, and clinical factors associated with the type of periodontal therapy (surgical vs. non-surgical re-treatment) to better inform multifactorial approaches in periodontal treatment planning. Methods: Electronic [...] Read more.
Background/Objectives: The aim of this retrospective cohort study was to identify and analyze the demographic, systemic, and clinical factors associated with the type of periodontal therapy (surgical vs. non-surgical re-treatment) to better inform multifactorial approaches in periodontal treatment planning. Methods: Electronic health records were analyzed to identify two distinct patient cohorts. The surgical cohort included patients who received one or more surgical procedures (i.e., gingival flap, osseous surgery). The non-surgical re-treatment cohort included patients who received scaling and root planing on more than one occasion and had no history of surgical treatment. Bivariate analyses (t-tests and Chi-square tests) were used to compare cohort characteristics, and a multivariable binary logistic regression model was developed to identify independent predictors of receiving surgical treatment. Results: A total of 3794 patients were included in the final analysis. The non-surgical re-treatment cohort presented with significantly more severe periodontal disease at baseline, including a higher number of bleeding sites and deep pockets (p < 0.001). The logistic regression analysis revealed that a higher number of bleeding sites (OR = 0.984) and deep pockets (OR = 0.987) were significantly associated with a decreased likelihood of receiving surgical treatment. Patients with high blood pressure (OR = 0.620) or arthritis (OR = 0.611) also had significantly lower odds of receiving surgery. Conversely, White patients had significantly higher odds (OR = 1.366) of receiving surgical therapy compared to non-White patients. Conclusions: Within the limitations of this study, the selection between surgical and non-surgical periodontal therapy is a multifactorial decision. Initial disease severity, specific systemic conditions, and patient race were significant predictors of the treatment provided. These findings highlight the necessity of adopting a multifactorial risk assessment framework in periodontology—one that integrates systemic and demographic risk factors alongside clinical parameters to tailor equitable, patient-specific care. Full article
(This article belongs to the Special Issue Personalized Dentistry: From Multidisciplinary Diagnosis to Precision Treatment)
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