Feature Papers to Celebrate the Inaugural Issue of Journal of Pharmaceutical and BioTech Industry

A special issue of Journal of Pharmaceutical and BioTech Industry (ISSN 2813-9380).

Deadline for manuscript submissions: 30 September 2025 | Viewed by 651

Special Issue Editor


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Guest Editor
Otto H. York Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA
Interests: particle engineering; pharmaceutical nanotechnology; drug nanosuspensions and nanocomposites; amorphous solid dispersions; multi-scale process modeling; pharmaceutical unit operations; milling; granulation; spray drying; extrusion
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Special Issue Information

Dear Colleagues,

The pharmaceutical and biotechnology industry continues to be one of the most important industry sectors for various reasons. It is essential for global health and the well-being of the public, as well as for the success of many countries’ economies. The discovery, development, manufacturing, and supply of pharmaceutical products, i.e., bench to bed, is one of the most versatile, multi-faceted, and innovative human endeavors. The aim of this Special Issue, titled "Feature Papers to Celebrate the Inaugural Issue of Journal of Pharmaceutical and BioTech Industry", is to highlight cutting-edge studies in all aspects of the discovery, development, delivery, and manufacturing of drugs. We invite all authors to contribute original research articles and timely review articles. This Special Issue of the Journal of Pharmaceutical and BioTech Industry is also expected to showcase contributions from scientists, engineers, and formulators in academia, industry, and regulatory agencies. Besides studies conducted by a single university, laboratory, or company, collaborative studies performed by multiple constituencies, e.g., academia–industry, academia–regulator, or academia–industry–regulator, are especially welcome, as are inter- or multi-disciplinary studies. The authors should consult the aims and scope of the Journal of Pharmaceutical and BioTech Industry for a more detailed scope of the journal.

Prof. Dr. Ecevit Bilgili
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • drug discovery
  • drug development
  • drug delivery
  • drug manufacturing
  • pharmaceutical and biotech industry
  • pharmaceutics
  • regulatory sciences

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Published Papers (1 paper)

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Review

34 pages, 1227 KiB  
Review
Non-Traditional Natural Stabilizers in Drug Nanosuspensions
by Simay Ozsoysal and Ecevit Bilgili
J. Pharm. BioTech Ind. 2024, 1(1), 38-71; https://doi.org/10.3390/jpbi1010005 - 13 Dec 2024
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Abstract
Poor solubility of many drugs, with ensuing low bioavailability, is a big challenge in pharmaceutical development. Nanosuspensions have emerged as a platform approach for long-acting injectables and solid dosages that enhance drug bioavailability. Despite improvements in nanosuspension preparation methods, ensuring nanosuspension stability remains [...] Read more.
Poor solubility of many drugs, with ensuing low bioavailability, is a big challenge in pharmaceutical development. Nanosuspensions have emerged as a platform approach for long-acting injectables and solid dosages that enhance drug bioavailability. Despite improvements in nanosuspension preparation methods, ensuring nanosuspension stability remains a critical issue. Conventionally, synthetic and semi-synthetic polymers and surfactants are used in nanosuspension formulations. However, no polymer or surfactant group is universally applicable to all drugs. This fact, as well as their toxicity and side effects, especially if used in excess, have sparked the interest of researchers in the search for novel, natural stabilizers. The objective of this paper is to provide a comprehensive analysis of non-traditional natural stabilizers reported in the literature published over the last decade. First, physical stability and stabilization mechanisms are briefly reviewed. Then, various classes of non-traditional natural stabilizers are introduced, with particular emphasis on their stabilization potential, safety, and pharmaceutical acceptability. Wherever data were available, their performance was compared with the traditional stabilizers. Furthermore, the benefits and limitations of using these stabilizers are examined, concluding with future prospects. This review is expected to serve as a valuable guide for researchers and formulators, offering insights into non-traditional natural stabilizers in drug nanosuspension formulations. Full article
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