Special Issue "Fungal Infections in the Developing World"
A special issue of Journal of Fungi (ISSN 2309-608X).
Deadline for manuscript submissions: closed (30 November 2016) | Viewed by 48675
Interests: epidemiology of invasive candidiasis and aspergillosis; epidemiology and molecular mechanisms of antifungal resistance; emerging fungal pathogens; new strategies for the diagnosis of fungal infections; new strategies for treating fungal infections
2. Serviço de Infectologia, Hospital de Clinicas da Universidade Federal do Paraná, Rua General Carneiro, 260, Curitiba, Paraná 80060-900, Brazil
Interests: endemic mycoses; mycoses of implantation; paracoccidioidomycosis; cryptococcois; inherited immunodeficiencies and mycoses
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Fungal infections have shaped the landscape of contemporary medicine worldwide due to a substantial increase in the population at risk, including organ transplant recipients, patients with neoplastic malignancies, individuals with chronic pulmonary infections, patients under immunosuppressive therapy, advanced ages, as well as critically ill patients requesting intensive care and indwelling medical devices.
In the setting of fungal health care associated infections, Candida and Aspergillus species remain the most common pathogens in different countries. Otherwise, considering the ever-increasing number of individuals presenting medical conditions associated to immunosuppression, the spectrum of opportunistic fungal agents able to cause systemic human infections has increased dramatically, including a large number of emerging yeasts (Thrichosporon spp, Rhodotorula spp, etc.) and molds (Fusarium spp, agents of mucormycosis, etc.). These infections are usually difficult to diagnose and hard to treat, and are associated with high mortality rates.
In addition to the high rate of nosocomial acquired fungal infections, developing countries present a large number of individuals exposed to agents of endemic mycoses. Agriculture is still the backbone of the economic growth of developing countries where there is a large number of people living in rural areas, as well as agricultural workers. Rural workers may get infected by true pathogenic soil-related fungi via direct inoculation into wounds or following the inhalation of bioaerosols containing fungal agents of endemic mycoces as paracoccidioidomycosis, histoplasmosis, and coccidioidomycosis. Unfortunatly, most medical centers from resource-limited countries are not appropriated equipped to early-diagnose and treat fungal infections, and patients with systemic mycoses usually present high rates of mortality and sequels.
Despite the substantial number of patients suffering from endemic and opportunistic mycoses living in our region, clinical and epidemiological data remain scarce and fragmentary. The objective of this Special Issue is to review the main epidemiological aspects of the most clinically significant systemic mycoses reported in developing countries, providing a critical evaluation of the burden of the disease, populations that are typically affected, and clinical outcomes. This information should be helpful, not only for academic proposals, but also to alert clinicians and public health authorities to take note of fungal infections.
The efforts of the Guest Editors to coordinate this special supplement is in consonance with our mission working for the Global Action Fund for Fungal Infection, in order to reduce illness and death associated with fungal diseases worldwide
Prof. Dr. Arnaldo Lopes Colombo
Dr. Flavio Queiroz Telles
Manuscript Submission Information
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- fungal infections
- Thrichosporon spp
- Rhodotorula spp
- Fusarium spp
- developing countries
- soil-related fungi
- resource-limited countries
- endemic and opportunistic mycoses