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Ecoepidemiology of Cryptococcus gattii in Developing Countries

1
Postgraduate Program in Microbiology, Parasitology and Pathology, Biological Sciences, Department of Basic Pathology, Federal University of Parana, Coronel Francisco Heráclito dos Santos Avenue, Jardim das Américas, 81531-980 Curitiba, Brazil
2
CAPES Foundation, Ministry of Education of Brazil, 70040-020 Brasília, Brazil
3
Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), 6532 SZ Nijmegen, The Netherlands
4
Centre of Expertise in Mycology Radboudumc/CWZ, 6532 SZ Nijmegen, The Netherlands
5
Laboratory of Mycology, Hospital de Clínicas, Federal University of Parana, 80060-000 Curitiba, Brazil
6
Communitarian Health Department, Hospital de Clínicas, Federal University of Parana, 80060-000 Curitiba, Brazil
*
Author to whom correspondence should be addressed.
J. Fungi 2017, 3(4), 62; https://doi.org/10.3390/jof3040062
Received: 27 September 2017 / Revised: 28 October 2017 / Accepted: 30 October 2017 / Published: 3 November 2017
(This article belongs to the Special Issue Fungal Infections in the Developing World)
Cryptococcosis is a systemic infection caused by species of the encapsulated yeast Cryptococcus. The disease may occur in immunocompromised and immunocompetent hosts and is acquired by the inhalation of infectious propagules present in the environment. Cryptococcus is distributed in a plethora of ecological niches, such as soil, pigeon droppings, and tree hollows, and each year new reservoirs are discovered, which helps researchers to better understand the epidemiology of the disease. In this review, we describe the ecoepidemiology of the C. gattii species complex focusing on clinical cases and ecological reservoirs in developing countries from different continents. We also discuss some important aspects related to the antifungal susceptibility of different species within the C. gattii species complex and bring new insights on the revised Cryptococcus taxonomy. View Full-Text
Keywords: Cryptococcus; cryptococcosis; reservoirs; developing countries; ecoepidemiology Cryptococcus; cryptococcosis; reservoirs; developing countries; ecoepidemiology
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MDPI and ACS Style

Herkert, P.F.; Hagen, F.; Pinheiro, R.L.; Muro, M.D.; Meis, J.F.; Queiroz-Telles, F. Ecoepidemiology of Cryptococcus gattii in Developing Countries. J. Fungi 2017, 3, 62.

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