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Special Issue "Effect of Lifestyle Habits on the Clinical Outcome in Trauma/Orthopedic Patients"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 1 September 2019

Special Issue Editor

Guest Editor
Dr. Sabrina Ehnert

Eberhard-Karls-Universität Tübingen, Tübingen, Germany
Website | E-Mail
Interests: cell culture; gene expression; medicinal and pharmaceutical chemistry; antioxidants; general surgery; reactive oxygen species; pharmacodynamics; traumatology; bone; bone metabolism; liver; diabetes; toxicology; glutathione; traumatology; osteoblasts; osteoclasts; mechanotransduction; hepatocytes

Special Issue Information

Dear Colleagues,

Lifestyle habits (e.g., daily diet, activity level, smoking, alcohol consumption) strongly affect bone health, often resulting in reduced bone quality and stability. In combination with an increased risk for falls, this strongly increases the fracture risk. In the case of a fracture, its treatment (fixation of the fracture, handling of the surrounding soft tissue, patients’ mobilization, etc.) represents a great challenge. Despite all medical progress, these patients still frequently face delayed or impaired bone healing rich in complications. This Special Issue should collect manuscripts that investigate the effect of lifestyle habits on fracture healing, reflecting our current knowledge and describing underlying molecular mechanisms that can provide novel diagnostic tools and treatment/therapeutic options.

Dr. Sabrina Ehnert
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Nutrition/daily diet
  • Mobility/exercise/activity level
  • Work intensity
  • Cigarette consumption
  • Alcohol consumption
  • Drug abuse
  • Sleep rhythm
  • Traveling/jet lag
  • Complications
  • Rehabilitation

Published Papers (1 paper)

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Open AccessArticle
Relationship between Sleep Duration and Osteoarthritis in Middle-Aged and Older Women: A Nationwide Population-Based Study
J. Clin. Med. 2019, 8(3), 356; https://doi.org/10.3390/jcm8030356
Received: 19 February 2019 / Revised: 8 March 2019 / Accepted: 11 March 2019 / Published: 13 March 2019
PDF Full-text (375 KB) | HTML Full-text | XML Full-text
(1) Background: Both long and short sleep durations have been associated with negative health outcomes, particularly in middle-aged and older adults. To date, there has been little research on the association between sleep and osteoarthritis. This study aimed to evaluate the relationship between [...] Read more.
(1) Background: Both long and short sleep durations have been associated with negative health outcomes, particularly in middle-aged and older adults. To date, there has been little research on the association between sleep and osteoarthritis. This study aimed to evaluate the relationship between sleep duration and radiographically confirmed osteoarthritis in middle-aged and older women. (2) Methods: This study included 5268 women aged ≥50 years from the Korea National Health and Nutrition Examination Survey. Sleep duration was categorized into four groups (≤5 h, 6 h, 7–8 h, and ≥9 h) using responses from a self-reported questionnaire, and 7–8 h was set as an appropriate sleep duration. Osteoarthritis was defined as Kellgren–Lawrence grade ≥2 in the knee or hip area in radiographic images with knee or hip joint pain. The odds ratios (ORs) and 95% confidence intervals (CIs) of osteoarthritis according to sleep duration were calculated using multiple logistic regression analyses. (3) Results: The prevalence of osteoarthritis according to sleep duration showed a U-shaped curve, with the nadir in the appropriate sleep category (7–8 h). Compared with the 7–8 h sleep duration, the ORs (95% CIs) of osteoarthritis in the short sleep duration (≤5 h/day) and long sleep duration (≥9 h/day) were 1.343 (1.072–1.682) and 1.388 (1.020–1.889), respectively, after adjusting for age, body mass index, current smoking, alcohol consumption, regular exercise, occupation, residential area, hypertension, type 2 diabetes, cardiovascular disease, and stroke. (4) Conclusions: Short and long sleep duration were positively associated with osteoarthritis in middle-aged and older women. Full article

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J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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