New Insights into Hypersensitivity Pneumonitis Diagnosis, Prognosis and Treatment

Dear Colleagues, 

Hypersensitivity pneumonitis is a diffuse lung disease which involves the small airways and the lungs and results from an exaggerated immune response to the inhalation of an antigen. The development and progression of the disease is variable and is the result of a complex interplay of genetic, host and environmental factors. Hypersensitivity pneumonitis may be classified as acute when symptoms occur abruptly after high level exposure or chronic when exposure is low and long-term, but more recently, classification has been based on the presence or absence of fibrosis, which allows a better stratification  according to different prognosis and clinical behavior, different CT pattern and different sensitivity for specific treatment options.

Although many questions about trigger factors, disease mechanism, adequate diagnosis and optimal treatment need to be solved, important progress has been made towards better understanding hypersensitivity pneumonitis. This Special Issue of the Journal of Clinical Medicine will focus on some recent advances that have been made on new inciting antigens, diagnosis, prognosis and treatment of hypersensitivity pneumonitis.

Prof. Johny Verschakelen
Guest Editor

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