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Special Issue "Diabetic Nephropathy: Diagnosis, Prevention and Treatment"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 25 December 2019

Special Issue Editors

Guest Editor
Prof. Dr. Marta Ruiz-Ortega

Molecular and Cellular Biology in Renal and Vascular Pathology. IIS-Fundación Jiménez Díaz-Universidad Autónoma Madrid, Spain; Red de Investigación Renal (REDINREN) Spain
Website | E-Mail
Interests: renal diseases; cardiovascular diseases; basic research; inflammation; fibrosis
Guest Editor
Dr. Raul Rodrigues-Diez

Molecular and Cellular Biology in Renal and Vascular Pathology. IIS-Fundación Jiménez Díaz-Universidad Autónoma Madrid, Spain; Red de Investigación Renal (REDINREN) Spain
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Interests: renal diseases; cardiovascular diseases; basic research; inflammation; fibrosis
Guest Editor
Dr. Sandra Rayego-Mateos

Vascular and Renal Translational Research Group. Institut de Recerca Biomèdica de Lleida (IRBLleida), Spain
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Interests: renal diseases; cardiovascular diseases; basic research; inflammation; fibrosis
Guest Editor
Dr. Carolina Lavoz

Division of Nephrology, School of Medicine, Universidad Austral, Valdivia, Chile
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Interests: renal diseases; cardiovascular diseases; basic research; inflammation; fibrosis

Special Issue Information

Dear Colleagues,

Chronic kidney disease (CKD) is a major health problem, because of its association with high cardiovascular risk and the progression to end-stage renal disease (ESRD) of most patients, requiring dialysis or transplantation. Diabetic nephropathy (DN) is the main cause of ESRD. DN is complex disease mediated by genetic and environmental factors. Initially, DN was considered a metabolic disease, but recent investigations have suggested the involvement of inflammation and immune cells in the pathogenesis of this disease. Recognized therapeutic strategies used in DN patients, including the strict control of glucose levels, blood pressure, and new anti-diabetic drugs, only retard renal damage progression, and there are no novel direct therapies for DN. Importantly, a barrier to progress is the lack of animal models resembling the main features of human DN, and future studies are needed. In addition, there are no biomarkers that reflect the severity of the underlying renal histopathological changes, and that can effectively predict the progression of renal damage and stratify the risk of DN among individuals with diabetes mellitus.

Prof. Dr. Marta Ruiz-Ortega
Dr. Raul Rodrigues-Diez
Dr. Sandra Rayego-Mateos
Dr. Carolina Lavoz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetic nephropathy
  • inflammation
  • fibrosis
  • immune cells
  • miRNAs
  • novel therapeutic targets
  • signaling systems
  • experimental models
  • biomarkers

Published Papers

This special issue is now open for submission.
J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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