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Current State of the Art in Breast Reconstruction
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Current State of the Art in Breast Reconstruction

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 668

Special Issue Editors

Dr. Ara A. Salibian

E-Mail Website
Guest Editor
Division of Plastic and Reconstructive Surgery, University of California Davis School of Medicine, Sacramento, CA 95817, USA
Interests: breast reconstruction; acellular dermal matrices; lymphatic surgery; microsurgery
Dr. David Daar

E-Mail Website
Guest Editor
Division of Plastic and Reconstructive Surgery, Keck School of Medicine of USC, Los Angeles, CA 90033, USA
Interests: breast reconstruction; lower-extremity reconstruction; microsurgery

Special Issue Information

Dear Colleagues,

Immediate breast reconstruction after breast cancer is known to improve the quality of life and survival in breast cancer patients. Multiple implant-based and autologous options for breast reconstruction after mastectomy are utilized today, as well as oncoplastic reconstruction techniques, during breast-conserving surgery. Reconstructive breast surgery continues to evolve as we strive to further minimize complications and optimize outcomes with these procedures. Furthermore, several areas of debate still exist in both spaces with regard to surgical decision-making and the choice of the optimal technique. This Special Issue of the Journal of Clinical Medicine reviews the “Current State of the Art in Breast Reconstruction”, focusing on contemporary gold standards in implant-based and autologous breast reconstruction, recent surgical advancements, new technology, current controversies, and future directions as we strive to continue to push this specialty forward.

Dr. Ara A. Salibian
Dr. David Daar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • breast reconstruction
  • microsurgery
  • breast cancer
  • breast implant
  • DIEP Flap

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Published Papers (2 papers)

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Review

20 pages, 2879 KiB  
Review
Optimizing Outcomes in Oncoplastic Breast-Conserving Surgery
by Aileen Gozali and Merisa Piper
J. Clin. Med. 2025, 14(13), 4806; https://doi.org/10.3390/jcm14134806 (registering DOI) - 7 Jul 2025
Abstract
Oncoplastic breast-conserving surgery (OBCS), or oncoplastic surgery, has revolutionized the surgical management of breast cancer by integrating oncologic principles with reconstructive techniques to optimize both cancer control and aesthetic outcomes following breast-conserving surgery (BCS). Since its inception in the 1980s, the field has [...] Read more.
Oncoplastic breast-conserving surgery (OBCS), or oncoplastic surgery, has revolutionized the surgical management of breast cancer by integrating oncologic principles with reconstructive techniques to optimize both cancer control and aesthetic outcomes following breast-conserving surgery (BCS). Since its inception in the 1980s, the field has evolved significantly, incorporating a range of volume displacement and volume replacement strategies to restore breast contour after partial mastectomy. This review explores the current practices and key surgical considerations of OBCS. It highlights the role of preoperative multidisciplinary planning, patient selection, anatomical and vascular knowledge, and intraoperative technique in optimizing results. Barriers to access—including disparities in training, insurance, and geographic availability—are addressed, alongside efforts by professional societies like the American Society of Breast Surgeons (ASBS) to standardize definitions and practices. The review also outlines strategies for minimizing complications and enhancing oncologic, reconstructive, and patient-reported outcomes. By offering a comprehensive framework for clinical decision-making, this paper aims to support broader adoption and refinement of OBCS as a standard component of breast cancer care. Full article
(This article belongs to the Special Issue Current State of the Art in Breast Reconstruction)
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17 pages, 529 KiB  
Review
Techniques for Success in Nipple-Sparing Mastectomy and Immediate Reconstruction
by Jenn J. Park, Carter J. Boyd, Kshipra Hemal, Thomas J. Sorenson, Chris Amro, Nicholas A. Vernice, Alexis C. Lakatta, Oriana Cohen, Mihye Choi and Nolan S. Karp
J. Clin. Med. 2025, 14(12), 4363; https://doi.org/10.3390/jcm14124363 - 19 Jun 2025
Viewed by 334
Abstract
Background: Nipple-sparing mastectomy (NSM), given demonstrated oncologic safety, is widely used for both therapeutic and prophylactic mastectomy. The popularity of NSM has spurred advancements by breast and plastic surgeons, liberalizing the indications for NSM and improving patient and aesthetic reconstructive outcomes. This review [...] Read more.
Background: Nipple-sparing mastectomy (NSM), given demonstrated oncologic safety, is widely used for both therapeutic and prophylactic mastectomy. The popularity of NSM has spurred advancements by breast and plastic surgeons, liberalizing the indications for NSM and improving patient and aesthetic reconstructive outcomes. This review explores these developments and establishes up-to-date surgical tenets for successful NSM and reconstruction. Methods: A comprehensive literature review was conducted using the PubMed, Google Scholar, and Cochrane Library databases, focusing on peer-reviewed studies published up to 2024. Articles were selected based on relevance, quantity, and documentation of clinical outcomes and patient satisfaction. Results: NSM is utilized frequently for both invasive breast cancers and prophylactic mastectomy, with expanded criteria for candidacy by breast surgeons. Staged procedures such as adjunct reduction, mastopexy, or nipple delay allow patients with larger or ptotic breasts to undergo NSM with comparable outcomes. Long-term outcome studies have identified important risk factors for complications, including smoking history, higher mastectomy weight, certain medical comorbidities, and suboptimal mastectomy flaps. Evolutions in reconstructive decision making in direct-to-implant and staged tissue expander placement have improved aesthetic results while accounting for poor mastectomy flap quality or adjuvant therapy. Long-term outcomes show NSM remains safe and has comparable rates of local recurrence. Patient-reported outcomes demonstrate satisfaction with NSM, especially in sexual and psychological wellbeing metrics. Conclusions: NSM has been demonstrated to be safe in long-term oncologic outcomes. Its widespread popularity over the past ten years has helped identify methods to improve upon surgical and aesthetic outcomes, including decision-making in reconstruction; considerations for challenging patient-related characteristics such as macromastia, ptosis, and NAC asymmetry; and novel advances in areas such as neurotization. Full article
(This article belongs to the Special Issue Current State of the Art in Breast Reconstruction)
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