Special Issue "Myocarditis in Clinical Practice"
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: closed (10 June 2022) | Viewed by 36900
Special Issue Editor
Interests: cardiomyopathies; myocarditis; heart failure
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Myocarditis is a major cause of cardiovascular disease, the causes, pathway, and treatment of which are in continuous evolution. It is a clinical syndrome which manifests with three major phenotypes: arrhythmic, infarct-like, and cardiomyopathic, which are sometimes difficult to identify with noninvasive tools, including cardiac magnetic resonance. Endomyocardial biopsy is still the gold standard for diagnosis, providing definitive information vital for prognosis and treatment. Indeed, the histology of endomyocardial tissue can be used to identify the various pathologic patterns of inflammatory lesions, while PCR on frozen samples can discriminate between possible agents. Different forms of myocarditis can thus be used as signals to identify various characteristics, such as infectious, hypersensitivity, granulomatous, giant cells, eosinophilic, associated to connective tissue, metabolic disorders, and virus-negative immune-mediated forms. Each form requires a specific treatment through which a partial or complete recovery are possible.
Finally, up to 15% of patients with myocarditis fail to respond to treatments based on accurate morpho-molecular characterizations. In these circumstances, an unnoticed, or possibly still unknown, infectious agent might be the cause. Metagenomics is a valuable approach for the identification of new agents.
Prof. Andrea Frustaci
Guest Editor
Manuscript Submission Information
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Keywords
- describing epidemiology
- causes
- pathways
- treatment
- metagenomics