Surgical Wound Infections and Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Rehabilitation".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 193

Special Issue Editors


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Guest Editor
Division of Trauma and Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD 21201, USA
Interests: soft tissue infections
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Division of Trauma and Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD 21201, USA
Interests: trauma; acute care surgery; wounds; open abdomen
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Surgical wound infections represent a significant challenge in postoperative care, contributing to extended hospital stays, increased medical costs, and heightened patient morbidity and mortality. We will provide a review of the state of our current knowledge of this problem. This Special Issue will explore the multifaceted aspects of these infections, providing a comprehensive resource for medical professionals.

Epidemiology and Incidence:

This section will cover the global and regional prevalence of surgical wound infections, highlighting trends and incidences. Understanding the epidemiology is crucial for developing targeted prevention strategies.

Groups Affected:

Focus will be given to vulnerable populations, including the elderly, immunocompromised patients, and those with comorbidities such as diabetes. This will shed light on risk factors and the need for tailored preventive measures. Burn wound infections are a particularly vexing problem. Approaches to the diagnosis and management of this difficulty problem will also be explored.

Medical and Surgical Treatments:

We will delve into the latest advancements in medical and surgical treatments, including prophylactic antibiotics, antiseptic techniques, guidelines, protocols, and innovative surgical approaches. Articles will explore evidence-based practices and emerging therapies aimed at reducing infection rates.

Outcomes and Complications:

We will examine the short- and long-term outcomes of surgical wound infections, addressing potential complications such as sepsis, delayed wound healing, and chronic pain. Understanding these outcomes is essential for improving patient care and recovery processes.

You may choose our Joint Special Issue in Bioengineering.

Prof. Dr. Sharon Henry
Prof. Dr. Marcelo A. F. Ribeiro Jr.
Guest Editors

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Keywords

  • surgical wound infections
  • epidemiology
  • incidence
  • risk factors
  • prophylactic antibiotics
  • antiseptic techniques
  • patient outcomes
  • complications
  • postoperative care
  • vulnerable populations
  • burn wound infection
  • antimicrobials
  • bioengineered materials for wounds and infections

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Published Papers (1 paper)

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Research

15 pages, 1145 KiB  
Article
Managing Necrotizing Soft Tissue Infections of the Lower Limb: Microsurgical Reconstruction and Hospital Resource Demands—A Case Series from a Tertiary Referral Center
by Georgios Karamitros, Michael P. Grant, Sharon Henry and Gregory A. Lamaris
J. Clin. Med. 2025, 14(9), 2997; https://doi.org/10.3390/jcm14092997 - 26 Apr 2025
Viewed by 115
Abstract
Background: Necrotizing soft tissue infections (NSTIs) of the lower extremities represent a surgical emergency with high morbidity, complex reconstruction, and considerable healthcare demands. Free tissue transfer (FTT) is increasingly utilized for limb salvage in extensive soft tissue defects, yet its implications for hospital [...] Read more.
Background: Necrotizing soft tissue infections (NSTIs) of the lower extremities represent a surgical emergency with high morbidity, complex reconstruction, and considerable healthcare demands. Free tissue transfer (FTT) is increasingly utilized for limb salvage in extensive soft tissue defects, yet its implications for hospital resource utilization remain unclear. This study aims to compare clinical outcomes and perioperative resource demands between FTT and local flap (LF) reconstruction in NSTI patients. Methods: A retrospective case series was conducted at a tertiary referral center between September 2022 and January 2025, including eight patients with NSTI of the lower extremity (FTT, n = 4; LF, n = 4). Demographic data, comorbidities, surgical timing, complication profiles, and resource utilization metrics—including operative duration, hospitalization length, and number of procedures—were analyzed. All FTT cases underwent preoperative CT angiography as part of institutional protocol. Results: Mean time to definitive reconstruction was longer in the FTT group (17.25 vs. 8 days, p = 0.15), reflecting staged infection control. FTT procedures demonstrated significantly longer operative times (331.75 vs. 170.25 minutes, p = 0.015), but there was no significant difference in total hospital stay (34.75 vs. 27.71 days, p = 0.65). No cases of flap loss or venous congestion were observed, and outcomes were optimized via delayed dangling protocols. Conclusions: FTT is a viable and effective reconstructive modality for lower extremity NSTIs. Despite increased surgical complexity, FTT did not significantly increase hospital resource utilization, supporting its role in limb preservation among appropriately selected patients. Full article
(This article belongs to the Special Issue Surgical Wound Infections and Management)
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