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Anesthesia and Intensive Care in Orthopedic and Trauma Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Intensive Care".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 476

Special Issue Editors


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Guest Editor
1. Department of Anesthesiology and Intensive Care II, Faculty of Medicine, Carol Davila University of Medicine and Pharmcy, 020021 Bucharest, Romania
2. Department of Anesthesiology and Intensive Care, Clinical Emergency Hospital, 010024 Bucharest, Romania
Interests: locoregional anesthesia; opioid sparing analgetic technique; pain management; patient blood management; hemostasis; transfusion; perioperative medicine; pain management in multiple trauma patients
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Guest Editor
Clinical Department No. 14, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: intensive care; pain management in intensive care; multiple trauma; nutrition in ICU patients; pharmacology

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Guest Editor Assistant
1. Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
2. Anesthesiology and Intensive Care Clinic, Clinical Emergency Hospital of Bucharest, Bucharest, Romania
Interests: intensive care; pain management in intensive care; multiple trauma; nutrition in ICU patients; pharmacology

Special Issue Information

Dear Colleagues,

The progress of locoregional anesthesia technique is remarkable. In this special issue, we aim to explore the multifaceted approaches to pain management in orthopedic and trauma patients, highlighting the critical role of early intervention, multimodal strategies, and individualized care. Various peripheral nerve blocks or comparment blocks, which were previously difficult to perform, have become more accurate using ultrasounds. In orthopedic surgery locoregional anesthesia and analgesia decrese the risk of perioperative delirium and perioperative opioid consumption. In this Special Issue, we welcome authors to submit original research papers and review articles on role of nerve blocks and regional anesthesia, non-invasive methods such as transcutaneous electrical nerve stimulation (TENS), use of emerging pharmacological agents or techniques (e.g., ketamine, cannabinoids), patient-controlled analgesia systems, adaptation of pain treatment in intensive care unit, balancing opioid use with the risk of addiction in post-surgical or trauma care, strategies for opioid-sparing pain management , pain management in the immediate post-injury phase vs. recovery phase, prevention and management of chronic pain following traumatic orthopedic injuries.

Dr. Liliana Mirea
Dr. Răzvan Ene
Guest Editors

Dr. Cristian Cobilinschi
Guest Editor Assistant 

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • opioid sparing analgetic technique
  • pain management
  • perioperative medicine
  • perioperative cognitive disfunction
  • delirium

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Published Papers (1 paper)

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Review

13 pages, 280 KiB  
Review
Integrating Peripheral Nerve Blocks in Multiple Trauma Care: Current Evidence and Clinical Challenges
by Liliana Mirea, Ana-Maria Dumitriu, Cristian Cobilinschi, Răzvan Ene and Raluca Ungureanu
J. Clin. Med. 2025, 14(15), 5598; https://doi.org/10.3390/jcm14155598 - 7 Aug 2025
Viewed by 252
Abstract
Pain management in multiple trauma patients presents a complex clinical challenge due to competing priorities such as hemodynamic instability, polypharmacy, coagulopathy, and the urgency of life-saving interventions. In this context, peripheral nerve blocks (PNBs) are increasingly recognized as a valuable asset for their [...] Read more.
Pain management in multiple trauma patients presents a complex clinical challenge due to competing priorities such as hemodynamic instability, polypharmacy, coagulopathy, and the urgency of life-saving interventions. In this context, peripheral nerve blocks (PNBs) are increasingly recognized as a valuable asset for their role in managing pain in patients with multiple traumatic injuries. By reducing reliance on systemic opioids, PNBs support effective pain control and facilitate early mobilization, aligning with enhanced recovery principles. This narrative review summarizes current evidence on the use of PNBs in the context of polytrauma, focusing on their analgesic efficacy, integration within multimodal analgesia protocols, and contribution to improved functional outcomes. Despite these advantages, clinical application is limited by specific concerns, including the potential to mask compartment syndrome, the risk of nerve injury or local anesthetic systemic toxicity (LAST), and logistical barriers in acute trauma settings. Emerging directions in the field include the refinement of ultrasound-guided PNB techniques, the expanded use of continuous catheter systems, and the incorporation of fascial plane blocks for anatomically complex or multisite trauma. Parallel efforts are focusing on the development of decision-making algorithms, improved risk stratification tools, and integration into multimodal analgesic pathways. There is also growing emphasis on standardized clinical protocols, simulation-based training, and patient education to enhance safety and consistency in practice. As evidence continues to evolve, the long-term impact of PNBs on functional recovery, quality of life, and healthcare utilization must be further explored. With thoughtful implementation, structured training, and institutional support, PNBs may evolve into a cornerstone of modern trauma analgesia. Full article
(This article belongs to the Special Issue Anesthesia and Intensive Care in Orthopedic and Trauma Surgery)
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