Next Article in Journal
Comparison of Endoscopic and Intraoperative Approaches in the Management of Delayed Gastric Conduit Emptying After Minimally Invasive Esophagectomy: A Single-Center Retrospective Analysis
Next Article in Special Issue
Incidence and Independent Risk Factors for Obstetric Anal Sphincter Injuries: A Four-Year Retrospective Cohort Study from a UK Tertiary Maternity Unit
Previous Article in Journal
Periodontal Status of Patients with Celiac Disease and Non-Celiac Gluten Sensitivity: A Literature Review
Previous Article in Special Issue
Phenotypes of Preterm Birth: A Retrospective Cohort Study from a Tertiary Romanian Centre as a Framework for Future Genomic and Proteomic Research
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Pregnancy Complications in Uterine Anomalies—A Pilot Study

by
Claudiu Voic
1,
Melinda Ildiko Mitranovici
2,*,
Septimiu Voidazan
3,
Cezara Maria Mureşan
4,5,6 and
Elena Silvia Bernad
4,5,6,7
1
Doctoral School, Victor Babes University of Medicine and Pharmacy from Timișoara, 300041 Timisoara, Romania
2
Department of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, Romania
3
Department of Epidemiology, “George Emil Palade” University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania
4
Department of Obstetrics and Gynecology, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania
5
Center for Laparoscopy, Laparoscopic Surgery and In Vitro Fertilization, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania
6
Clinic of Obstetrics and Gynecology, Laparoscopy, In Vitro Fertilization and Embryotransfer Research Center, Pius Brinzeu County Clinical Emergency Hospital, 300723 Timisoara, Romania
7
Center for Neuropsychology and Behavioral Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2026, 15(8), 2827; https://doi.org/10.3390/jcm15082827
Submission received: 4 March 2026 / Revised: 2 April 2026 / Accepted: 5 April 2026 / Published: 8 April 2026

Abstract

Uterine malformation represents a rare disease with a prevalence of up to 7% of the general population. Background/Objectives: Higher pregnancy complication rates have been reported in the literature; thus, in our study, we aimed to examine not only the obstetric complications encountered but also the psychological interventions and multidisciplinary approaches for parental counseling in our department in the context of preterm birth at the limit of viability. Methods: A retrospective pilot study was conducted on all the women in our department between 2010 and 2017 with congenital uterine malformations associated with infertility or pregnancy. In the study group, we included women with AUCs (n = 26), while the control group included pregnant women with normal uteri (n = 25) (total: n = 51), and then pregnancy complications were investigated. Results: Highly significant pregnancy complications were observed in the study group, the most important being preterm birth (p = 0.003) in comparison with the control group. Out of 26 patients with AUCs, only 14 gave birth to a live fetus compared to 22 out of the 25 with normal pregnancies, meaning that failure to give birth to a live newborn statistically significantly increased among the former group (p = 0.004). In terms of birth weight (p = 0.0001), Apgar score (p = 0.029) and intensive care unit admission (p = 0.0001), we observed significant differences between the newborns in the study group versus controls, with an impact on mental state that required psychological support. Conclusions: A clear correlation was observed in our study between uterine congenital malformations and pregnancy complications. The most common pregnancy outcome was premature delivery, with statistical significance. In addition, higher neonate admissions to the intensive care unit associated with lower Apgar scores were encountered compared with normal pregnancies. Appropriate parental counseling by obstetricians, neonatologists and psychologists could enhance pregnancy outcomes.
Keywords: uterine anomalies; pregnancy complications; limit of viability; prenatal counseling; mental health uterine anomalies; pregnancy complications; limit of viability; prenatal counseling; mental health

Share and Cite

MDPI and ACS Style

Voic, C.; Mitranovici, M.I.; Voidazan, S.; Mureşan, C.M.; Bernad, E.S. Pregnancy Complications in Uterine Anomalies—A Pilot Study. J. Clin. Med. 2026, 15, 2827. https://doi.org/10.3390/jcm15082827

AMA Style

Voic C, Mitranovici MI, Voidazan S, Mureşan CM, Bernad ES. Pregnancy Complications in Uterine Anomalies—A Pilot Study. Journal of Clinical Medicine. 2026; 15(8):2827. https://doi.org/10.3390/jcm15082827

Chicago/Turabian Style

Voic, Claudiu, Melinda Ildiko Mitranovici, Septimiu Voidazan, Cezara Maria Mureşan, and Elena Silvia Bernad. 2026. "Pregnancy Complications in Uterine Anomalies—A Pilot Study" Journal of Clinical Medicine 15, no. 8: 2827. https://doi.org/10.3390/jcm15082827

APA Style

Voic, C., Mitranovici, M. I., Voidazan, S., Mureşan, C. M., & Bernad, E. S. (2026). Pregnancy Complications in Uterine Anomalies—A Pilot Study. Journal of Clinical Medicine, 15(8), 2827. https://doi.org/10.3390/jcm15082827

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop