Current Advances and Unmet Needs in Autoimmune Inflammatory Rheumatic Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology & Rheumatology".
Deadline for manuscript submissions: 20 January 2027 | Viewed by 153
Editor
Interests: rheumatoid arthritis; disease-modifying antirheumatic drugs; inflammatory rheumatic disease; interstitial lung disease; bronchietasis; infectious disease; MASLD/MASH
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autoimmune inflammatory rheumatic diseases (AIIRDs) are a large and heterogeneous group of conditions that share common underlying pathogenetic features but also present unique clinical features such as clinically diverse phenotypes, demographic characteristics, organ system involvement, and therapeutic response. These diseases include rheumatoid arthritis, spondyloarthritis-spectrum diseases, and connective tissue disorders, among others.
AIIRDs are currently incurable, but the availability of novel immune-targeted therapeutics, as well as stringent inflammation control, has dramatically improved quality of life and longevity for patients with AIIRDs. However, there remain many unmet medical needs, such as issues regarding primary or secondary unresponsiveness, adverse effects, and long-term drug maintenance. It is essential that we address these unmet needs to improve therapeutic outcomes in AIIRD patients.
The aim of this Special Issue is to provide the latest research findings and clinical advancements in diagnosis, comorbidities, and treatment strategies using biologic and nonbiologic immune-targeted therapies for AIIRDs and to address many unmet needs that continue to beleaguer the management of AIIRD patients. I welcome high-quality original research papers and comprehensive reviews that enhance our awareness and understanding of these challenging conditions and contribute to developing new ideas and future research directions on novel immune-targeted therapeutics for AIIRDs.
Dr. Shunsuke Mori
Guest Editor
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Keywords
- autoimmune inflammatory rheumatic diseases
- rheumatoid arthritis
- connective tissue disorders
- comorbidities
- unmet medical needs
- immune-targeted therapies
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