Insights into Left Bundle Branch Pacing Mechanics and Efficacy
A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Electrophysiology and Cardiovascular Physiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 445
Special Issue Editor
Interests: pacemakers; ICDs; cardiac conduction system pacing; pulse filed ablation; atrial fibrillation
Special Issue Information
Dear Colleagues,
Left bundle branch area pacing (LBBAP) has emerged as a promising modality within conduction system pacing (CSP), offering a more accessible and technically feasible alternative to His bundle pacing (HBP), while maintaining favorable electrical parameters and long-term pacing stability. However, while LBBAP shows encouraging clinical outcomes, much remains unknown about the mechanical and functional effects it induces on the ventricular myocardium.
The left bundle branch (LBB) area is anatomically complex and extensive, encompassing the main trunk as well as anterior, posterior, and septal fascicles. Depending on the exact pacing site—whether in the proximal trunk, one of the fascicles, or even deep within the left septal subendocardial region—mechanical synchronization, electrical activation, and overall myocardial work efficiency may vary significantly. These physiological nuances are not yet fully understood and warrant in-depth investigation.
This Special Issue welcomes the submission of original research articles, reviews, and case studies that provide insights into ventricular mechanics, electromechanical coupling, myocardial work efficiency, and clinical outcomes associated with various LBBAP pacing strategies. We particularly welcome contributions that explore advanced imaging techniques, computational modeling, and long-term follow-up data to elucidate these dynamics.
Dr. Francesco Vitali
Guest Editor
Manuscript Submission Information
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Keywords
- left bundle branch area pacing
- conduction system pacing
- ventricular mechanics
- myocardial work efficiency
- septal pacing
- cardiac resynchronization therapy
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